Art

J-GLOBAL ID：200902102067058711   Reference number：02A0357537

Antisense oligodeoxynucleotides against thrombomodulin suppress the cell growth of lung adenocarcinoma cell line A549.

トロンボモジュリンに対するアンチセンスオリゴデオキシヌクレオチドは肺腺癌細胞系A549の細胞増殖を抑制する

Author (4)： FUJIWARA M (Nippon Medical School, Kawasaki, JPN) ,  JIN E (Nippon Medical School, Kawasaki, JPN) ,  GHAZIZADEH M (Nippon Medical School, Kawasaki, JPN) ,  KAWANAMI O (Nippon Medical School, Kawasaki, JPN)
Material： Pathology International  (Pathol Int)
Volume： 52  Issue： 3  Page： 204-213  Publication year： Mar. 2002 
JST Material Number： W0853A  ISSN： 1320-5463  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *antisense nucleotide ,...

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JST classification (2)： Basic oncology in general  (GE02010R) ,  Gene manipulation  (EC02050B)

Reference (42)：

• ESMON, NL. Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C. J. Biol. Chem. 1982, 257, 859-864
• SUZUKI, K. Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. EMBO J. 1987, 6, 1891-1897
• JACKMAN, RW. Human thrombomodulin gene is intron depleted : nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control. Proc. Natl Acad. Sci. USA. 1987, 84, 6425-6429
• FUENTES-PRIOR, P. Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex. Nature. 2000, 404, 518-525
• ESMON, CT. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J. Biol. Chem. 1989, 264, 4743-4746

Terms in the title (6)： トロンボモジュリン ,  アンチセンスオリゴデオキシヌクレオチド ,  肺腺癌 ,  細胞系 ,  A549 ,  細胞増殖