Art

J-GLOBAL ID：200902102716647322   Reference number：98A0153457

Gene therapy and viral vectors. Adeno-associated virus vectors and gene therapy.

遺伝子治療用ウイルスベクターの開発と展望 アデノ随伴ウイルスベクターと遺伝子治療

Author (2)： URABE MASASHI (自治医大) ,  OZAWA KEIYA (自治医大)
Material： ウイルス  (Virus)
Volume： 47  Issue： 2  Page： 221-230  Publication year： Dec. 1997 
JST Material Number： Z0769A  ISSN： 0042-6857  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *adeno-associated virus ,...
Semi thesaurus term： chromosome 19 ,...

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JST classification (2)： Therapeutics in general  (GC03011J) ,  Gene manipulation  (EC02050B)

Reference (59)：

• 1) Alexander, I. E., Russell, D. W., and Miller, A. D. (1994) DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors. J Virol 68, 8282-8287.
• 2) Alexander, I. E., Russell, D. W., Spence, A. M., and Miller, A. D. (1996) Effects of gamma irradiation on the transduction of dividing and nondividing cells in brain and muscle of rats by adeno-associated virus vectors. Hum Gene Ther 7, 841-850.
• 3) Balagué C., Kalla, M., and Zhang, W. W. (1997) Adeno-associated virus Rep78 protein and terminal repeats enhance integration of DNA sequences into the cellular genome. J Virol 71, 3299-3306.
• 4) Batchu, R. B., and Hermonat, P. L. (1995) The trans-inhibitory Rep78 protein of adeno-associated virus binds to TAR region DNA of the human immunodeficiency virus type 1 long terminal repeat. FEBS Lett 361, 267-271.
• 5) Batchu, R. B., Kotin, R. M., and Hermonat, P. L. (1994) The regulatory rep protein of adeno-associated virus binds to sequences within the c-H-ras promoter. Cancer Lett 86, 23-31.

Terms in the title (5)： 遺伝子治療 ,  ウイルスベクター ,  開発 ,  展望 ,  アデノ随伴ウイルスベクター