Inhibition of Anchorage-Independent Growth of Tumor Cells by IT-62-B, a New Anthracycline.

S.-TSUCHIYA K; ISHII T; IKENO S; KUNIMOTO S; KAWAUCHI T; OTANI T; HORI M

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J-GLOBAL ID：200902102814709255 Reference number：97A1019169

Inhibition of Anchorage-Independent Growth of Tumor Cells by IT-62-B, a New Anthracycline.

新規アントラサイクリン,IT-62-Bによる培地無影響腫よう細胞成長抑制

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Author (7)： , , , , , ,
Material：
Volume： 50 Issue： 10 Page： 853-859 Publication year： Oct. 1997
JST Material Number： G0489A ISSN： 0021-8820 Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Basic research of antitumor(=antineoplastic)antibiotics

Reference (8)：

1) TSUCHIYA, S. K.; T. KANBE, M. HORI, Y. UEHARA, Y. TAKAHASHI & T. TAKEUCHI: Distinct effects of clinically used anthracycline antibiotics on ras oncogene-expressed cells. Biol. Pharm. Bull. 16: 908-911, 1993
2) KAWAUCHI, T.; T. SASAKI, K. YOSHIDA, H. MATSUMOTO, R.-X. CHEN, M.-Y. HUANG, K. S.-TSUCHIYA& T. OTANI: A new anthracycline antibiotic, IT-62-B, converts the morphology of ms-transformed cells back to normal: Taxonomy, fermentation, isolation, structure elucidation and biological characterization. J. Antibiotics 50: 297-303, 1997
3) SEKIYA, T.; V. S. PRASSOLOV, M. FUSHIMI & S. NISHIMURA: Transforming activity of the c-Ha-ras oncogene having two point mutations in codons 12 and 61. Jpn. J. Cancer Res. (Garni)-76: 851-855, 1985
4) TAYA, Y.; K. HOSOGAI, S. HIROHASHI, Y. SHIMOSATO, R. TSUCHIYA, N. TSUCHIDA, M. FUSHIMI, T. SEKIYA & S. NISHIMURA: A novel combination of K-ras and myc amplification accompanied by point mutational activation of K-ras in a human lung cancer. EMBO J. 3: 2943-2946, 1984
5) WINNACKER, E. L.; G. MAGNUSSON & P. REICHARD: Replication of polyoma DNA in isolated nuclei. I. Characterization of the system from mouse fibroblast 3T6 cells. J.Mol. Biol. 72: 523-537, 1972

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