Role of p53 Gene in Apoptotic Repair of Genotoxic Tissue Damage in Mice.

KATO F; KAKIHARA H; KUNUGITA N; OOTSUYAMA A; NORIMURA T

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J-GLOBAL ID：200902102823451066 Reference number：03A0368375

Role of p53 Gene in Apoptotic Repair of Genotoxic Tissue Damage in Mice.

遺伝毒によるマウス組織障害のアポトーシス修復におけるp53遺伝子の働き

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Material：
Volume： 43 Issue： Supplement Page： S209-S212 Publication year： Dec. 2002
JST Material Number： F0337A ISSN： 0449-3060 CODEN： JRARAX Document type： Article
Article type：解説 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Influence on animals , Molecular genetics in general

Reference (13)：

WANG, B. Involvement of p53-dependent apoptosis in radiation teratogenesis and in the radioadaptive response in the late organogenesis of mice. J. Radiat. Res. 2001, 42, 1-10
TAKAHASHI, A. Pre-irradiation at a low dose-rate blunted p53 response. J. Radiat. Res. 2002, 43, 1-9
NORIMURA, T. p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med. 1996, 2, 577-580
KATO, F. Threshold effect for teratogenic risk of radiation depends on dose-rate and p53-dependent apoptosis. Int. J. Radiat. Biol. 2001, 77, 13-19
UMEKI, S. Flow cytometric measurements of somatic cell mutations in Thorotrast patients. Jpn. J. Cancer Res. 1991, 82, 1349-1353

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