Secretion of heterologous proteins by Aspergillus niger: Production of active human interleukin-6 in a protease-deficient mutant by KEX2-like processing of a glucoamylase-hIL6 fusion protein.

BROEKHUIJSEN M P; MATTERN I E; CONTRERAS R; KINGHORN J R; VAN DEN HONDEL C A M J J

Art

J-GLOBAL ID：200902104448703950 Reference number：94A0011720

Secretion of heterologous proteins by Aspergillus niger: Production of active human interleukin-6 in a protease-deficient mutant by KEX2-like processing of a glucoamylase-hIL6 fusion protein.

黒色麹菌による外来蛋白質の分泌生産プロテアーゼ欠失変異株を用いたグルコアミラーゼ-hIL6融合蛋白質のKEX2-様プロセシングによる活性型ヒトインターロイキン-6の生産

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Author (5)： , , , ,
Material：
Volume： 31 Issue： 2 Page： 135-145 Publication year： Nov. 1993
JST Material Number： A0456C ISSN： 0168-1656 Document type： Article
Article type：原著論文 Country of issue： Netherlands (NLD) Language： ENGLISH (EN)

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Microbial metabolite production , Gene manipulation

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