Art

J-GLOBAL ID：200902105358779016   Reference number：02A0236725

Bromocriptine Reverses P-Glycoprotein-mediated Multidrug Resistance in Tumor Cells.

ブロモクリプチンは腫よう細胞のP糖蛋白質仲介多剤耐性を解除する

Author (8)： SHIRAKI N (Kumamoto Univ. Hospital, Kumamoto) ,  OKAMURA K (Kumamoto Univ. Hospital, Kumamoto) ,  TOKUNAGA J (Kumamoto Univ. Hospital, Kumamoto) ,  OHMURA T (Kumamoto Univ. Hospital, Kumamoto) ,  YASUDA K (Kumamoto Univ. Hospital, Kumamoto) ,  KAWAGUCHI T (Josai Univ., Saitama) ,  HAMADA A (Kumamoto Univ. Hospital, Kumamoto) ,  NAKANO M (Kumamoto Univ. Hospital, Kumamoto)
Material： Japanese Journal of Cancer Research  (Proceedings. Annual Meeting of the Japanese Cancer Association)
Volume： 93  Issue： 2  Page： 209-215  Publication year： Feb. 28, 2002 
JST Material Number： F0633A  ISSN： 0910-5050  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *dopaminergic drug ,...
Semi thesaurus term： calcium channel blocker ,...

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JST classification (2)： Drugs acting on autonomic nervous system in general  (GW05010O) ,  Transport of cell membrane  (EF04020R)

Substance index (7)： Bromocriptine ,  Doxorubicin ,  Vincristine ,  Ciclosporin ,  Verapamil hydrochloride ,  Vinorelbine ,  Etoposide

Reference (23)：

• JULIANO, R. L. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta. 1976, 455, 152-162
• FOJO, A. Localization of multidrug resistance-associated DNA sequences to human chromosome 7. Somat. Cell Mol. Genet. 1986, 12, 415-420
• CHEN, C. J. Internal duplication and homology with bacterial transport proteins in the mdrl (P-glycoprotein) gene from multidrug-resistant human cells. Cell. 1986, 47, 381-389
• GOTTESMAN, M. M. The multidrug-transporter, a double-edged sword. J. Biol. Chem. 1988, 263, 12163-12166
• GROS, P. Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell. 1986, 47, 371-380

Terms in the title (5)： ブロモクリプチン ,  腫よう細胞 ,  P糖蛋白質 ,  仲介 ,  多剤耐性