Art

J-GLOBAL ID：200902105753455319   Reference number：01A0058532

多発性骨髄腫の骨吸収病変に対するビスフォスフォネートの効果

Author (7)： HASHIMOTO TOSHIHIRO (徳島大) ,  ABE MASAHIRO (徳島大) ,  ISHITA SHUN (徳島大) ,  SHIBATA YASUNOBU (徳島大) ,  OGASAWARA KOJI (徳島大) ,  OZAKI SHUJI (徳島大) ,  MATSUMOTO TOSHIO (徳島大)
Material： 日本内分泌学会雑誌  (Folia Endocrinologica Japonica)
Volume： 76  Issue： Suppl.  Page： 46-49  Publication year： Oct. 20, 2000 
JST Material Number： F0915A  ISSN： 0029-0661  CODEN： NNGZAZ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *Multiple Myeloma ,...
Semi thesaurus term： bisphosphonate

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JST classification (2)： Hematologic diseases  (GK03000F) ,  Drug therapy(=pharmacotherapy)for musculoskeletal diseases  (GG05020D)

Reference (6)：

• BATAILLE, R. Quantifiable excess of bone resorption in monoclonal gammopathy is an early symptom of malignancy: a prospective study of 87 bone biopsoes. Blood. 1996, 87, 4762-4769
• PECHERSTORFER, M. Bone resorption in multiple myeloma and in monoclonal gammopathy of undetermined significance: quantification by urinary pyridinium cross-links of collagen. Blood. 1997, 90, 3743-3750
• BERENSON, J. R. Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group. N Engl J Med. 1996, 334, 488-493
• FISHER, J. E. Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. Proc Natl Acad Sci U S A. 1999, 96, 133-138
• LUCKMAN, S. P. Nitrogen-containing bishosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res. 1998, 13, 581-589

Terms in the title (4)： 多発性骨髄腫 ,  骨吸収 ,  病変 ,  ビスフォスフォネート