Art

J-GLOBAL ID：200902107184751470   Reference number：01A0921819

Evaluation of the Potential of p-Boronophenylalaninol as a Boron Carrier in Boron Neutron Capture Therapy, Referring to the Effect on Intratumor Quiescent Cells.

腫よう内静止細胞に対する効果に注目したほう素中性子捕獲療法におけるほう素担体としてのp-ボロノフェニルアラニノールの可能性の評価

Author (9)： MASUNAGA S (Kyoto Univ., Osaka) ,  ONO K (Kyoto Univ., Osaka) ,  KIRIHATA M (Osaka Prefecture Univ., Osaka) ,  TAKAGAKI M (Kyoto Univ., Osaka) ,  SAKURAI Y (Kyoto Univ., Osaka) ,  KINASHI Y (Kyoto Univ., Osaka) ,  KOBAYASHI T (Kyoto Univ., Osaka) ,  NAGASAWA H (Univ. Tokushima, Tokushima) ,  HORI H (Univ. Tokushima, Tokushima)
Material： Japanese Journal of Cancer Research  (Proceedings. Annual Meeting of the Japanese Cancer Association)
Volume： 92  Issue： 9  Page： 996-1007  Publication year： Sep. 30, 2001 
JST Material Number： F0633A  ISSN： 0910-5050  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *boron isotope ,...
Semi thesaurus term： resting cell

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JST classification (2)： Basic research of radiopharmaceuticals  (GW18010O) ,  Basic oncology in general  (GE02010R)

Substance index (3)： Phenylalanine ,  Borofalan 10B ,  (S)-3-[4-[Dihydroxy(¹⁰B)boryl]phenyl]-2-amino-1-propanol

Reference (24)：

• CODERRE, J. A. The radiation biology of boron neutron capture therapy. Radiat. Res. 1999, 151, 1-18
• KIRIHATA, M. Synthesis and biological evaluation of boron-containing animo alcohols as potential boron carriers on BNCT. Kyoto University Research Reactor Institute Progress Report 1998,. 1998, 174
• KIRIHATA, M. Development of new boron carriers for BNCT. Synthesis and biological evaluation of both enantiomers of p-boronophenylalaninol. Kyoto University Research Reactor Institute Progress Report 1999. 1999, 156
• BROWN, J. M. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 1998, 58, 1408-1416
• SIEMANN, D. W. The tumor microenvironment: a double-edged sword. Int. J. Radiat. Oncol. Biol. Phys. 1998, 42, 697-699

Terms in the title (8)： 腫よう ,  静止細胞 ,  注目 ,  ほう素中性子捕獲療法 ,  ほう素 ,  担体 ,  可能性 ,  評価