Targeted disruption of Skp2 results in accumulation of cyclin E and p27<sup>Kip1</sup>, polyploidy and centrosome overduplication.

NAKAYAMA K; NAGAHAMA H; MINAMISHIMA Y A; MATSUMOTO M; NAKAMICHI I; KITAGAWA K; SHIRANE M; TSUNEMATSU R; HATAKEYAMA S

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J-GLOBAL ID：200902107840606105 Reference number：00A0620532

Targeted disruption of Skp2 results in accumulation of cyclin E and p27^Kip1, polyploidy and centrosome overduplication.

Skp2遺伝子の標的化破壊はサイクリンE及びp27^Kip1の蓄積,倍数性及び中心体過剰重複をもたらす

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Author (9)： , , , , , , , ,
Material：
Volume： 19 Issue： 9 Page： 2069-2081 Publication year： May. 02, 2000
JST Material Number： A0911B ISSN： 0261-4189 CODEN： EMJODG Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Biological function , Cell physiology in general

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Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication.

Targeted disruption of Skp2 results in accumulation of cyclin E and p27^Kip1, polyploidy and centrosome overduplication.