Art

J-GLOBAL ID：200902111120496784   Reference number：00A0682981

Studies on the binding mechanism of fluoroquinolones to melanin.

メラニンへのフルオロキノロンの結合機構に関する研究

Author (4)： FUKUDA M (Kanazawa Medical Univ., Ishikawa, JPN) ,  SASAKI K (Kanazawa Medical Univ., Ishikawa, JPN) ,  MORITA Y (Tohoku Pharmaceutical Univ., Sendai, JPN) ,  YAMAMOTO Y (Tohoku Pharmaceutical Univ., Sendai, JPN)
Material： Journal of Infection and Chemotherapy  (J Infect Chemother)
Volume： 6  Issue： 2  Page： 72-76  Publication year： Jun. 2000 
JST Material Number： L2852A  ISSN： 1341-321X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *biopigment ,...
Semi thesaurus term： メラニン類似物質

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JST classification (1)： Basic research of antibacterial drugs  (GW17020S)

Substance index (11)： Melanin ,  Norfloxacin ,  Ciprofloxacin ,  Lomefloxacin ,  Ofloxacin ,  Levofloxacin ,  Phenylalanine ,  Tyrosine ,  L-Dopa ,  Tryptophan ,  5-Hydroxytryptophan

Reference (21)：

• BARZA, M. Marked differences between pigmented and albino rabbits in the concentration of clindamycin in iris and choroid-retina. J Infect Dis. 1979, 139, 203-8
• POTTS, AM. The reaction of uveal pigment in vitro with polycyclic compounds. Invest Ophthalmol Vis Sci. 1964, 3, 405-16
• BARZA, M. Inhibition of antibiotic activity in vitro by synthetic melanin. Antimicrob Agents Chemother. 1976, 10, 569-70
• SALAZAR, M. Iris pigmentation and atropine mydriasis. J Pharmacol Exp Ther. 1976, 197, 79-88
• ATLASIK, B. Interaction of drugs with ocular melanin in vitro. Exp Eye Res. 1980, 30, 325-31

Terms in the title (3)： メラニン ,  フルオロキノロン ,  研究