Art

J-GLOBAL ID：200902113398856806   Reference number：99A0402157

Benzodiazepine Receptor Agonists Modulate Thymocyte Apoptosis Through Reduction of the Mitochondrial Transmembrane Potential.

ベンゾジアゼピン受容体作動薬はミトコンドリアの経膜電位減少により胸腺細胞のアポトーシスを調節する

Author (4)： TANIMOTO Y (Tokyo Dental Coll., Chiba, JPN) ,  ONISHI Y (Tokyo Dental Coll., Chiba, JPN) ,  SATO Y (Tokyo Dental Coll., Chiba, JPN) ,  KIZAKI H (Tokyo Dental Coll., Chiba, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 79  Issue： 2  Page： 177-183  Publication year： Feb. 1999 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： benzodiazepine receptor ,...
Semi thesaurus term： *benzodiazepine tranquilizer

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JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic research of psychotropic drugs  (GW03100Y)

Substance index (6)： Diazepam ,  Clonazepam ,  PK-11195 ,  1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine ,  Dexamethasone ,  Etoposide

Reference (29)：

• 1 Costa E and Guidotti A: Molecular mechanisms in the receptor action of benzodiazepines. Annu Rev Pharmacol Toxicol 19, 531 - 543 (1979)
• 2 Pawlikowski M: Immunomodulating effects of peripherally acting benzodiazepines. In Peripheral Benzodiazepine Receptors, Edited by Giessen-Crouse E, pp 125 - 135, Academic Press, New York (1993)
• 3 Woods MJ and Williams DC: Multiple forms and locations for the peripheral-type benzodiazepine receptor. Biochem Pharmacol 52, 1805 - 1814 (1996)
• 4 Le Fur G, Perrier ML, Vaucher N, Imbault F, Flamier J, Benavides J, Uzan A, Renaut C, Dubroeucq MC and Gueremy C: Peripheral benzodiazepine binding sites: Effects of PK 11195, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline-carboxamide. I. In vivo studies. Life Sci 32, 1839 - 1847 (1983)
• 5 Zoratti M and Szabo I: The mitochondrial permeability transition. Biochim Biophys Acta 1241, 139 - 176 (1995)

Terms in the title (6)： ベンゾジアゼピン受容体作動薬 ,  ミトコンドリア ,  経膜電位 ,  胸腺細胞 ,  アポトーシス ,  調節