Art

J-GLOBAL ID：200902114973736741   Reference number：99A0313886

Inhibition of IL-6 and IL-8 induction from cultured rheumatoid synovial fibroblasts by treatment with aurothioglucose.

アウロチオグルコース(AuTG)処理による培養リウマチ滑膜線維芽細胞(RSF)由来IL6,IL8誘導の抑制

Author (8)： YOSHIDA S (Nagoya City Univ. Medical School, Nagoya, JPN) ,  KATO T (Nagoya City Univ. Medical School, Nagoya, JPN) ,  SAKURADA S (Nagoya City Univ. Medical School, Nagoya, JPN) ,  KURONO C (Nagoya City Univ. Medical School, Nagoya, JPN) ,  YANG J-P (Nagoya City Univ. Medical School, Nagoya, JPN) ,  MATSUI N (Nagoya City Univ. Medical School, Nagoya, JPN) ,  SOJI T (Nagoya City Univ. Medical School, Nagoya, JPN) ,  OKAMOTO T (Nagoya City Univ. Medical School, Nagoya, JPN)
Material： International Immunology  (Int Immunol)
Volume： 11  Issue： 2  Page： 151-158  Publication year： Feb. 1999 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *antirheumatic drug ,...
Semi thesaurus term： rheumatoid arthritis

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JST classification (1)： Basic research of anti-inflammatory drugs  (GW15010T)

Substance index (1)： Aurothioglucose

Reference (36)：

• MUKAIDA, N. Cooperative interaction of nuclear factor-kappa B and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J. Biol. Chem. 1990, 265, 21128
• SCHRECK, R. NF-kappa B as inducible transcriptional activator of the granulocyte-macrphage colony-strimulating factor gene. Mol. Cell. Biol. 1990, 10, 1281
• LIBERMANN, T. A. Activation of interleukin-6 gene expression through the NF- kappa B transcription factor. Mol. Cell. Biol. 1990, 10, 2327
• SAKURADA, S. Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin. Int. Immunol. 1996, 8, 1483
• HANDEL, M. L. Nuclear factor-κB in rheumatoid synovium. Arthritis Rheum. 1995, 38, 1762

Terms in the title (7)： アウロチオグルコース ,  培養 ,  リウマチ ,  滑膜線維芽細胞 ,  IL6 ,  IL8 ,  誘導