Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.

FARESE R V JR; RULAND S L; FLYNN L M; STOKOWSKI R P; YOUNG S G

Art

J-GLOBAL ID：200902117138005565 Reference number：95A0339256

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.

マウスアポリポ蛋白質B遺伝子のノックアウトは同型接合体でははい死亡を生じ,異型接合体では食餌誘発性高コレステロール血症の抑制を引起こす

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Author (5)： , , , ,
Material：
Volume： 92 Issue： 5 Page： 1774-1778 Publication year： Feb. 28, 1995
JST Material Number： D0387A ISSN： 0027-8424 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Biological function , Gene manipulation

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