Art

J-GLOBAL ID：200902117775756027   Reference number：01A0511680

Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice.

マウス局所脳虚血後のミトコンドリアからのcytochrome c漏出とアポトーシス SOD-2の役割について

Author (6)： FUJIMURA MIKI (東北大 医 脳神経外科) ,  MORITA(FUJIMURA) YUIKO (Stanford Univ. School of Medicine, California) ,  KAWASE MAKOTO (東北大 医 脳神経外科) ,  KONDO TAKEO (東北大 医 脳神経外科) ,  YOSHIMOTO TAKASHI (東北大 医 脳神経外科) ,  CHAN P H (Stanford Univ. School of Medicine, California)
Material： 脳卒中  (日本脳卒中学会機関誌)
Volume： 22  Issue： 3  Page： 472-476  Publication year： Sep. 25, 2000 
JST Material Number： X0160A  ISSN： 0912-0726  Document type： Article
Article type： 会議録記事  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *cerebral ischemia ,...

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JST classification (2)： Basic neurology  (GN01020W) ,  Enzyme physiology  (EJ02020P)

Reference (10)：

• CHAN, P. H. Role of oxidants in ischemic brain damage. Stroke. 1996, 27, 1124-1129
• FUJIMURA, M. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci. 1999, 19, 3414-3422
• FUJIMURA, M. Copper, zinc-superoxide dismutase prevents the early decrease of apurinic /apyrimidinic endonuclease and subsequent DNA fragmentation after focal cerebral ischemia in mice. Stroke. 1999, 30, 2408-2415
• FUJIMURA, M. Early decrease of XRCC 1, a DNA base excision repair protein, may contribute to DNA fragmentation after transient focal cerebral ischemia in mice. Stroke. 1999, 30, 2456-2463
• FUJIMURA, M. Cytosolic antioxidant Cu/Zn SOD prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. J Neurosci. 2000, 20, 2817-2824

Terms in the title (7)： マウス ,  局所脳虚血 ,  ミトコンドリア ,  漏出 ,  アポトーシス ,  SOD ,  役割