Art

J-GLOBAL ID：200902117830530602   Reference number：98A0902255

Synthesis and Antiallergic Activity of Dimethyl-2-(phenylcarbamoyl)ethylsulfonium p-Toluenesulfonate Derivatives.

ジメチル-2-(フェニルカルバモイル)エチルスルホニウムp-トルエンスルホネート誘導体の合成と抗アレルギー活性

Author (8)： TADA Y (Taiho Pharmaceutical Co., Ltd., Saitama, JPN) ,  YAMAWAKI I (Taiho Pharmaceutical Co., Ltd., Saitama, JPN) ,  UEDA S (Taiho Pharmaceutical Co., Ltd., Tokushima, JPN) ,  MATSUMOTO H (Taiho Pharmaceutical Co., Ltd., Tokushima, JPN) ,  MATSUURA N (Taiho Pharmaceutical Co., Ltd., Tokushima, JPN) ,  YASUMOTO M (Taiho Pharmaceutical Co., Ltd., Saitama, JPN) ,  KODA A (Gifu Pharmaceutical Univ., Gifu, JPN) ,  HORI M (Gifu Pharmaceutical Univ., Gifu, JPN)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 41  Issue： 18  Page： 3330-3336  Publication year： Aug. 27, 1998 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *antiallergic action ,...
Semi thesaurus term： B lymphocyte ,...

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JST classification (2)： Basic research of histaminergic drugs and antihistaminergic drugs  (GW06010V) ,  Aliphatic sulfoxides,sulfones,sulfonium compounds  (CF03150Y)

Substance index (24)： Suplatast tosilate ,  rac-Dimethyl[3-[[4-[(R^*)-2-hydroxy-3-methoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2-hydroxy-3-propoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2-hydroxy-3-butoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2-hydroxy-3-(cyclohexyloxy)propoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2-hydroxy-3-phenoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-(phenylamino)-3-oxopropyl]sulfonium ,  Dimethyl[3-[[4-(trifluoromethyl)phenyl]amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-acetylphenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-chlorophenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-fluorophenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[[4-(carboxymethyl)phenyl]amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-methylphenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-methoxyphenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-hydroxyphenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[(4-propoxyphenyl)amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[[4-(2,3-dihydroxypropoxy)phenyl]amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[[4-(3-hydroxypropyl)phenyl]amino]-3-oxopropyl]sulfonium ,  Dimethyl[3-[[4-(2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2,3-dimethoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2,3-diethoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[4-[(R^*)-2-acetoxy-3-ethoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[2-[(R^*)-2-acetoxy-3-ethoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium ,  rac-Dimethyl[3-[[3-[(R^*)-2-acetoxy-3-ethoxypropoxy]phenyl]amino]-3-oxopropyl]sulfonium

Terms in the title (4)： ジメチル ,  スルホニウム ,  誘導体 ,  抗アレルギー活性