Art

J-GLOBAL ID：200902117968708780   Reference number：02A0245270

Five New Chromones Possessing Monoamine Oxidase Invibitor Activity from an Ascomycete, Chaetomium quadrangulatum.

子嚢菌類、Chaetomium quadrangulatumからの、モノアミンオキシダーゼ阻害活性を有する5種の新しいクロモン類

Author (4)： FUJIMOTO H (Chiba Univ., Chiba, JPN) ,  NOZAWA M (Chiba Univ., Chiba, JPN) ,  OKUYAMA E (Chiba Univ., Chiba, JPN) ,  ISHIBASHI M (Chiba Univ., Chiba, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 50  Issue： 3  Page： 330-336  Publication year： Mar. 01, 2002 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *oxygen heterocyclic compound ,...
Semi thesaurus term： Chaetomium quadrangulatum

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JST classification (2)： Condensed derivatives of pyrane  (CF07093I) ,  Microorganism biochemistry  (EG03020N)

Substance index (12)： Chaetoquadrin A ,  Acetic acid (2R,3R)-3α,6′α,8-trimethyl-5-methoxy-10-oxo-3,3′,4,4′,5′,6′-hexahydrospiro[2H,10H-benzo[1,2-b:3,4-b′]dipyran-2,2′-[2H]-pyran]-4′α-yl ester ,  (R)-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid (2R,3R)-3α,6′α,8-trimethyl-5-methoxy-10-oxo-3,3′,4,4′,5′,6′-hexahydrospiro[2H,10H-benzo[1,2-b:3,4-b′]dipyran-2,2′-[2H]-pyran]-4′α-yl ester ,  (S)-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid (2R,3R)-3α,6′α,8-trimethyl-5-methoxy-10-oxo-3,3′,4,4′,5′,6′-hexahydrospiro[2H,10H-benzo[1,2-b:3,4-b′]dipyran-2,2′-[2H]-pyran]-4′α-yl ester ,  Chaetoquadrin B ,  Chaetoquadrin C ,  Chaetoquadrin D ,  ChaetoquadrinE ,  2-Methyl-5-hydroxy-6-[2-[(4S)-2,2,6α-trimethyl-1,3-dioxane-4β-yl]ethyl]-7-methoxy-4H-1-benzopyran-4-one ,  (R)-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid (1S,3S)-1-methyl-3-hydroxy-5-(2-methyl-4-oxo-5-hydroxy-7-methoxy-4H-1-benzopyran-6-yl)pentyl ester ,  (S)-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid (1S,3S)-1-methyl-3-hydroxy-5-(2-methyl-4-oxo-5-hydroxy-7-methoxy-4H-1-benzopyran-6-yl)pentyl ester ,  2-Methyl-5-hydroxy-6-(hydroxymethyl)-7-methoxychromone

Reference (18)：

• SATOH, Y. Chem. Pharm. Bull. 1989, 37, 206-207
• FUJIMOTO, H. Heterocycles. 1990, 30, 607-616
• YOSHIDA, E. Chem. Pharm. Bull. 1996, 44, 284-287
• YOSHIDA, E. Natural Med. 1996, 50, 54-57
• YOSHIDA, E. Chem. Pharm. Bull. 1996, 44, 1775

Terms in the title (5)： 子嚢菌類 ,  Chaetomium ,  モノアミンオキシダーゼ ,  阻害活性 ,  クロモン類