Art

J-GLOBAL ID：200902120366746746   Reference number：00A0139297

Influence of Chronic Treatment With Imipramine on mRNA Levels in Rat Brain. Elevation of Glyceraldehyde-3-phosphate Dehydrogenase Levels.

ラット脳でのmRNA値に対するイミプラミンでの長期投与の影響 グリセルアルデヒド-3-りん酸デヒドロゲナーゼ値の上昇

Author (3)： TOHDA M (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  QI Z (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  WATANABE H (Toyama Medical and Pharmaceutical Univ., Toyama, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 81  Issue： 4  Page： 393-396  Publication year： Dec. 01, 1999 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *tricyclic antidepressive drug ,...

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JST classification (2)： Basic research of psychotropic drugs  (GW03100Y) ,  Central nervous system  (EJ12030F)

Substance index (1)： Imipramine

Reference (15)：

• 1 Barker EL and Blakely RD: Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with human serotonin transporter. Mol Pharmacol 50, 957 - 965 (1996)
• 2 Tohda M and Watanabe H: Imipramine-induced increase in 5-HT2C receptor mRNA level in the rat brain. Neurosci Res 24, 189 - 193 (1996)
• 3 Tohda M and Watanabe H: Enhancement of serotonin 2C receptor mRNA expression by antidepressants possessing the receptor-blocking activity in the rat brain. Jpn J Pharmacol 78, 515 - 517 (1998)
• 4 Tohda M, Nomura Y and Watanabe H: Effects of imipramine on 5-HT2C mRNA and a novel depression related gene (DRF24) expression. Soc Neurosci Abstr 22, 943 (1996)
• 5 Chomczynski P and Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162, 156 - 159 (1987)

Terms in the title (6)： ラット ,  脳 ,  mRNA ,  イミプラミン ,  長期投与 ,  グリセルアルデヒド-3-りん酸デヒドロゲナーゼ