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J-GLOBAL ID:200902121403510177   Reference number:01A0488467

Mechanism of Sodium Load-Induced Hypertension in Non-Insulin Dependent Diabetes Mellitus Model Rat: Defective Dopaminergic System to Inhibit Na-K-ATPase Activity in Renal Epithelial Cells.

非インシュリン依存糖尿病モデルラットにおけるナトリウム負荷が誘導する高血圧の機構 腎臓上皮細胞におけるNa-K-ATPアーゼ活性を阻害するドーパミン系の欠損
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Material:
Volume: 24  Issue:Page: 127-135  Publication year: Mar. 2001 
JST Material Number: Y0303A  ISSN: 0916-9636  Document type: Article
Article type: 原著論文  Country of issue: Germany, Federal Republic of (DEU)  Language: ENGLISH (EN)
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Metabolic diseases,nutritional diseases in general.  ,  Basic medicine on cardiovascular system 
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Reference (37):
  • 1. Landsberg L: Pathophysiology of obesity-related hypertension: role of insulin and the sympathetic nervous system. J Cardiovasc Pharmacol 1994; 23 (Suppl I): S1-S8.
  • 2. Rocchini AP, Katch V, Kveselis D, et al: Insulin and renal sodium retention in obese adolescents. Hypertension 1989; 14: 367-374.
  • 3. Rowe JW, Young JB, Minaker KL, Stevens AL, Pallotta J, Landsberg L: Effect of insulin and glucose infusion on sympathetic nervous system activity in normal man. Diabetes 1981; 30: 219-225.
  • 4. Meehan WP, Buchanan TA, Hsueh W: Chronic insulin administration elevates blood pressure in rats. Hypertension 1994; 23: 1012-1017.
  • 5. Campese VM, Romoff MS, Levitan D, Saglikes Y, Friedler RM, Massry SG: Abnormal relationship between sodium intake and sympathetic nervous system activity in salt-sensitive patients with essential hypertension. Kidney Int 1982; 21: 371-378.
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