Art

J-GLOBAL ID：200902122619869460   Reference number：01A1058187

Effect of lactational exposure to 1,2,3,4- tetrachlorodibenzo-p-dioxin on cytochrome P-450 1A1 mRNA in the neonatal rat liver: Quantitative analysis by the competitive RT-PCR method.

ラット新生児肝臓のチトクロームP-450 1A1 mRNAに及ぼす授乳期の1,2,3,4-テトラクロロジベンゾ-p-ダイオキシンの影響:きっ抗的RT-PCR法による定量解析

Author (8)： KONO Y (Tottori Univ., Yonago, JPN) ,  OKADA S (Tottori Univ., Yonago, JPN) ,  TAZAWA Y (Tottori Univ., Yonago, JPN) ,  KANZAKI S (Tottori Univ., Yonago, JPN) ,  MURA T (Tottori Univ., Yonago, JPN) ,  UETA E (Tottori Univ., Yonago, JPN) ,  NANBA E (Tottori Univ., Yonago, JPN) ,  OTSUKA Y (Tottori Univ., Yonago, JPN)
Material： Pediatrics International  (Pediatr Int)
Volume： 43  Issue： 5  Page： 458-464  Publication year： Oct. 2001 
JST Material Number： Z0373B  ISSN： 1328-8067  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Rattus ,...
Semi thesaurus term： CYP1A1 ,...

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JST classification (3)： Enzyme in general  (EB09010D) ,  Other pollutants  (SB05040W) ,  Gene expression  (EC02040Q)

Substance index (1)： 2,3,7,8-TCDD

Reference (28)：

• RAPPE, C. Assessment of human exposure to polychlorinated dibenzofurans and dioxins. Environ. Health Perspect. 1985, 60, 303-304
• VANDEN HEUVEL, JP. Accumulation of polychlorinated dibenzo-p-dioxins and dibenzofurans in liver of control laboratory rats. Fundam. Appl. Toxicol. 1994, 23, 465-469
• MANSON, G. Polychlorinated dibenzo-p-dioxins: Quantitative in vitro and in vivo structure-activity relationships. Toxicology. 1986, 41, 21-31
• LOVELL, DP. Quantitative risk assessment and the limitations of the linearized multistage model. Hum. Exp. Toxicol. 1996, 15, 87-104
• SEO, BW. Effects of gestational and lactational exposure to coplanar polychlorinated biphenyl (PCB) congeners or 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) on thyroid hormone concentrations in weanling rats. Toxicol. Lett. 1995, 78, 253-262

Terms in the title (10)： ラット ,  新生児 ,  肝臓 ,  チトクロームP-450 ,  mRNA ,  授乳期 ,  ダイオキシン ,  きっ抗 ,  RT-PCR法 ,  定量解析