Art

J-GLOBAL ID：200902123504914999   Reference number：02A0662487

Design and Synthesis of a Novel Class of Sugar-Peptide Hybrids: C-Linked Glyco β-Amino Acids through a Stereoselective “Acetate” Mannich Reaction as the Key Strategic Element.

新系列の糖-ペプチド複合体の設計と合成 キー戦略要素として立体選択的“アセテート”Mannich反応を経由するC-結合グリコβ-アミノ酸

Author (9)： PALOMO C (Univ. Pais Vasco, San Sebastian, ESP) ,  OIARBIDE M (Univ. Pais Vasco, San Sebastian, ESP) ,  LANDA A (Univ. Pais Vasco, San Sebastian, ESP) ,  GONZALEZ-REGO C (Univ. Pais Vasco, San Sebastian, ESP) ,  GARCIA J M (Univ. Publica de Navarra, Pamplona, ESP) ,  GONZALEZ A (Univ. Publica de Navarra, Pamplona, ESP) ,  ODRIOZOLA J M (Univ. Publica de Navarra, Pamplona, ESP) ,  MARTIN-PASTOR M (Univ. Santiago de Compostela, Coruna, ESP) ,  LINDEN A (Univ. Zuerich, Zuerich, CHE)
Material： Journal of the American Chemical Society  (J Am Chem Soc)
Volume： 124  Issue： 29  Page： 8637-8643  Publication year： Jul. 24, 2002 
JST Material Number： C0254A  ISSN： 0002-7863  CODEN： JACSAT  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *amino acid ,...

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JST classification (1)： Glycosides  (CF10057O)

Substance index (16)： 1-[(1R,4S)-2α-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane-2-yl]ethanone ,  N-[1-(p-Tolylsulfonyl)-3-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)propyl]carbamic acid benzyl ester ,  N-[1-(p-Tolylsulfonyl)-3-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-galactopyranosyl)propyl]carbamic acid benzyl ester ,  N-[1-(p-Tolylsulfonyl)-3-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-mannopyranosyl)propyl]carbamic acid benzyl ester ,  N-[1-(p-Tolylsulfonyl)-3-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)propyl]carbamic acid tert-butyl ester ,  N-[1-(p-Tolylsulfonyl)-3-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-galactopyranosyl)propyl]carbamic acid tert-butyl ester ,  N-[1-(p-Tolylsulfonyl)-3-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-mannopyranosyl)propyl]carbamic acid tert-butyl ester ,  (S)-3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)valeric acid methyl ester ,  (S)-3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-galactopyranosyl)valeric acid methyl ester ,  (S)-3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-mannopyranosyl)valeric acid methyl ester ,  (R)-3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)valeric acid methyl ester ,  3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)valeric acid methyl ester ,  3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-galactopyranosyl)valeric acid methyl ester ,  3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-mannopyranosyl)valeric acid methyl ester ,  (S)-3-[[N-(tert-Butyloxycarbonyl)-L-phenylalanyl]amino]-5-(α-D-glucopyranosyl)valeric acid methyl ester ,  (S)-3-[[(S)-3-[(Benzyloxycarbonyl)amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)pentanoyl]amino]-5-(2-O,3-O,4-O,6-O-tetrabenzyl-α-D-glucopyranosyl)valeric acid

Terms in the title (10)： 系列 ,  糖 ,  ペプチド複合体 ,  設計 ,  キー ,  戦略 ,  要素 ,  立体 ,  Mannich反応 ,  β-アミノ酸