The presenilin 2 mutation(N141I) linked to familial Alzheimer disease(Volga German families) increases the secretion of amyloid β protein ending at the 42nd(or 43rd) residue.

TOMITA T; MARUYAMA K; SAIDO T C; KUME H; SHINOZAKI K; TOKUHIRO S; CAPELL A; WALTER J; OBATA K

Art

J-GLOBAL ID：200902123552586235 Reference number：97A0358822

The presenilin 2 mutation(N141I) linked to familial Alzheimer disease(Volga German families) increases the secretion of amyloid β protein ending at the 42nd(or 43rd) residue.

家族性Alzheimer病(Volga German家系)関連プレセニリン2変異(N141I)は42位(あるいは43位)アミノ酸残基で終わるアミロイドβ蛋白質の分泌を増加させる

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Material：
Volume： 94 Issue： 5 Page： 2025-2030 Publication year： Mar. 04, 1997
JST Material Number： D0387A ISSN： 0027-8424 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Gene expression , Basic neurology

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