Art

J-GLOBAL ID：200902126023419942   Reference number：95A0922408

Antimalarial activity of new ethers and thioethers of dihydroartemisinin.

ジヒドロアルテミシニンの新しいエーテル類とチオエーテル類の抗マラリア作用

Author (6)： VENUGOPALAN B (Hoechst India Ltd., Bombay, IND) ,  KARNIK P J (Hoechst India Ltd., Bombay, IND) ,  BAPAT C P (Hoechst India Ltd., Bombay, IND) ,  CHATTERJEE D K (Hoechst India Ltd., Bombay, IND) ,  IYER N (Hoechst India Ltd., Bombay, IND) ,  LEPCHA D (Hoechst India Ltd., Bombay, IND)
Material： European Journal of Medicinal Chemistry  (Eur J Med Chem)
Volume： 30  Issue： 9  Page： 697-706  Publication year： 1995 
JST Material Number： E0845A  ISSN： 0223-5234  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： antimalarial drug ,...
Semi thesaurus term： Plasmodium yoelii nigeriensis ,...

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JST classification (2)： Basic research of antiprotozoan drugs and anthelmintics  (GW17080G) ,  Seven-membered heterocyclic compounds  (CF07110I)

Substance index (22)： [[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]glycidyl ether ,  1-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]oxy]-3-(diethylamino)-2-propanol ,  2-[2-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]oxy]ethoxy]ethanol ,  2-[2-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10α-yl]oxy]ethoxy]ethanol ,  N-[2-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]oxy]ethyl]phthalimide ,  2-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]oxy]ethanamine ,  Propenoic acid 2-[[[(3R,5aα,8aα,12aR)-decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]oxy]ethyl ester ,  3-Piperidinopropionic acid 2-[[[(3R,5aα,8aα,12aR)-decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]oxy]ethyl ester ,  [[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10α-yl]ethyl sulfide ,  [[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]ethyl sulfide ,  [[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]cyclohexyl sulfide ,  [[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10α-yl]cyclohexyl sulfide ,  (3R,5aα,8aα,12aR)-3,6α,9β-Trimethyl-10β-(phenylthio)-3β,12α-epoxydecahydropyrano[4,3-j]-1,2-benzodioxepin ,  (3R,5aα,8aα,12aR)-3,6α,9β-Trimethyl-10α-(phenylthio)-3β,12α-epoxydecahydropyrano[4,3-j]-1,2-benzodioxepin ,  2-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]thio]acetic acid ,  3-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]thio]propionic acid ,  2-[[[(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin]-10β-yl]thio]ethanamine ,  (3R,5aα,8aα,12aR)-3,6α,9-Trimethyl-9-bromo-10β-ethoxydecahydro-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin ,  (3R,5aα,8aα,12aR)-3,6α,9-Trimethyl-9-bromo-10β-(2-propenyloxy)decahydro-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin ,  (3R,5aα,8aα,12aR)-3,6α,9-Trimethyl-9-bromo-10β-(2-propynyloxy)decahydro-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin ,  (3R,5aα,8aα,12aR)-Decahydro-9-bromo-10β-(ethylthio)-3,6α,9-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin ,  (3R,5aα,8aα,12aR)-Decahydro-9-bromo-10β-(phenylthio)-3,6α,9-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin

Terms in the title (4)： ジヒドロアルテミシニン ,  エーテル類 ,  チオエーテル類 ,  抗マラリア作用