Art

J-GLOBAL ID：200902127000803733   Reference number：01A0372635

Identification of multiple sources of charge heterogeneity in a recombinant antibody.

組み換え抗体中の電荷不均一性複合ソースの同定

Author (9)： HARRIS R J (Genentech Inc., CA, USA) ,  KABAKOFF B (Genentech Inc., CA, USA) ,  MACCHI F D (Genentech Inc., CA, USA) ,  SHEN F J (Genentech Inc., CA, USA) ,  KWONG M (Genentech Inc., CA, USA) ,  JAMES D (Genentech Inc., CA, USA) ,  SHIRE S J (Genentech Inc., CA, USA) ,  TOTPAL K (Genentech Inc., CA, USA) ,  CHEN A B (Genentech Inc., CA, USA)
Material： Journal of Chromatography B. Biomedical Sciences and Applications  (Journal of Chromatography B. Biomedical Application)
Volume： 752  Issue： 2  Page： 233-245  Publication year： Mar. 10, 2001 
JST Material Number： W0571A  ISSN： 0378-4347  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *ion exchange chromatography ,...
Semi thesaurus term： peptide map ,...

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JST classification (2)： Biophysical research methods  (EA03020V) ,  Antigens,antibodies,complements in general  (ED04010A)

Substance index (2)： Asparagine ,  Aspartic Acid

Reference (35)：

• EDELMAN, G. M. Proc. Natl. Acad. Sci. USA. 1969, 63, 237
• TAKAHASI, N. Biochemistry. 1987, 26, 1137
• KROON, D. J. Pharm. Res. 1992, 9, 1386
• HARRIS, R. J. Bio/Technol. 1993, 11, 1293
• LIFELY, M. R. Glycobiol. 1995, 5, 813

Terms in the title (5)： 組み換え抗体 ,  電荷 ,  不均一性 ,  ソース ,  同定