Art

J-GLOBAL ID：200902129052401105   Reference number：99A0893677

Decatromicins A and B, New Antibiotics Produced by Actinomadura sp. MK73-NF4. II. Structure Determination.

デカトロミシンAとB,Actinomadura sp.MK73-NF4が生産する新しい抗生物質 II 構造決定

Author (7)： MOMOSE I (Inst. Microbial Chemistry, Tokyo, JPN) ,  HIROSAWA S (Inst. Microbial Chemistry, Tokyo, JPN) ,  NAKAMURA H (Inst. Microbial Chemistry, Tokyo, JPN) ,  NAGANAWA H (Inst. Microbial Chemistry, Tokyo, JPN) ,  IINUMA H (Inst. Microbial Chemistry, Tokyo, JPN) ,  IKEDA D (Inst. Microbial Chemistry, Tokyo, JPN) ,  TAKEUCHI T (Inst. Microbial Chemistry, Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 52  Issue： 9  Page： 787-796  Publication year： Sep. 25, 1999 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： NMR spectrometer ,...
Semi thesaurus term： *Actinomadura ,...

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JST classification (1)： Antibiotics in general  (GX01000E)

Substance index (12)： Decatromicin A ,  Decatromicin B ,  (21β)-7-O-[4-[[(5-Chloro-1H-pyrrole-2-yl)carbonyl]amino]-2,4,6-trideoxy-β-D-glucopyranosyl]-6α,16,18α,28,31-pentamethyl-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide ,  (21β)-7-O-[4-[[(1H-Pyrrole-2-yl)carbonyl]amino]-2,4,6-trideoxy-β-D-glucopyranosyl]-6α,16,18α,28,31-pentamethyl-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide ,  (21β)-6α,16,18α,28,31-Pentamethyl-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide ,  (21β)-6α,16,18α,28,31-Pentamethyl-20-(methoxycarbonyl)-20-descarboxy-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide ,  1-O-Methyl-4-[[(3,5-dichloro-1H-pyrrole-2-yl)carbonyl]amino]-2,4,6-trideoxy-α-D-arabino-hexopyranose ,  1-O-Methyl-4-[[(3,5-dichloro-1H-pyrrole-2-yl)carbonyl]amino]-2,4,6-trideoxy-β-D-arabino-hexopyranose ,  1-O-Methyl-3-O-(4-bromobenzoyl)-4-[[(3,5-dichloro-1H-pyrrole-2-yl)carbonyl]amino]-2,4,6-trideoxy-α-D-arabino-hexopyranose ,  (21β)-6α,16,18α,24-O,28,31-Hexamethyl-20-(methoxycarbonyl)-20-descarboxy-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide ,  (21β)-7-O-[(R)-2-Methoxy-2-phenyl-3,3,3-trifluoropropionyl]-6α,16,18α,24-O,28,31-hexamethyl-20-(methoxycarbonyl)-20-descarboxy-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide ,  (21β)-7-O-[(S)-2-Methoxy-2-phenyl-3,3,3-trifluoropropionyl]-6α,16,18α,24-O,28,31-hexamethyl-20-(methoxycarbonyl)-20-descarboxy-13,14-didehydro-2,25-carbonyl-25-des(formyloxy)-1,2-secochlorothricolide

Reference (13)：

• 1) MOMOSE, L; H. IINUMA, N. KINOSHITA, Y. MOMOSE, S. KUNIMOTO, M. HAMADA & T. TAKEUCHI: Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. I. Taxonomy, isolation, physico-chemical properties and biological activities. J. Antibiotics 52: 781-786, 1999
• 2) MALLAMS, A. K.; M. S. PUAR & R. R. ROSSMAN: Kijanimicin. Part 3. Structure and absolute stereochemistry of kijanimicin. J. Chem. Soc. Perkin Trans. I. 1497-1534, 1983
• 3) KORAN, A. C.; M. C. SHEARER, V HEGDE, M. L. BEYAZOA, B. C. BRODSKY, A. KING, R. BERRIE, K. CARDACI & M. NIMECK: A family of novel macro-cyclic lactones, the saccarocarcins produced by Saccarothrix aerocolonigenes subsp. antibiotica. I. Taxonomy, fermentation, isolation and biological properties. J. Antibiotics 50: 119-125, 1997
• 4) HEGDE, V R.; M. G. PATEL, P. R. DAS, B. PRAMANIK & M. S. PUAR: A family of novel macrocyclic lactones, the saccarocarcins produced by Saccarothrix aerocolonigenes subsp. antibiotica. II. Physico-chemical properties and structure determination. J. Antibiotics 50: 126-134, 1997
• 5) LAM, K. S.; G. A. HESLER, D. R. GUSTASON, R. L. BERRY, K. TOMITA, J. L. MACBETH, J. Ross, D. MILLER & S. FORENZA: Pyrrolosporin A, a new antitumor antibiotic from Micromonospora sp. C39217-R109-7. I. Taxonomy of producing organism, fermentation and biological activity. J. Antibiotics 49: 860-864, 1996

Terms in the title (2)： Actinomadura ,  抗生物質