Aspartate 313 in the Streptomyces plicatus Hexosaminidase Plays a Critical Role in Substrate-assisted Catalysis by Orienting the 2-Acetamido Group and Stabilizing the Transition State.

WILLIAMS S J; MARK B L; VOCADLO D J; JAMES M N G; WITHERS S G

Art

J-GLOBAL ID：200902136776143260 Reference number：02A0905396

Aspartate 313 in the Streptomyces plicatus Hexosaminidase Plays a Critical Role in Substrate-assisted Catalysis by Orienting the 2-Acetamido Group and Stabilizing the Transition State.

Streptomyces plicatusのヘキソサミニダーゼのアスパラギン酸313は2-アセトアミド基を方向付け,遷移状態を安定化することにより基質支援触媒に重要な役割を果たす

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Author (5)： , , , ,
Material：
Volume： 277 Issue： 42 Page： 40055-40065 Publication year： Oct. 18, 2002
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Biological function , Enzyme in general , Metabolism in general

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