Art

J-GLOBAL ID：200902137559505037   Reference number：01A0116416

X-Ray Crystal Structure and Catalytic Properties of Thr252Ile Mutant of Cytochrome P450cam: Roles of Thr252 and Water in the Active Center.

チトクロームP450camThr252Ile変異体のX線結晶構造と触媒特性

Author (9)： HISHIKI T (Keio Univ., Tokyo) ,  SHIMADA H (Keio Univ., Tokyo) ,  NAGANO S (Keio Univ., Tokyo) ,  EGAWA T (Keio Univ., Tokyo) ,  KANAMORI Y (Keio Univ., Tokyo) ,  MAKINO R (Keio Univ., Tokyo) ,  ADACHI S (RIKEN Harima Inst., Hyogo) ,  SHIRO Y (RIKEN Harima Inst., Hyogo) ,  ISHIMURA Y (Keio Univ., Tokyo)
Material： Journal of Biochemistry  (J Biochem)
Volume： 128  Issue： 6  Page： 965-974  Publication year： Dec. 01, 2000 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Pseudomonas putida ,...

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JST classification (1)： Enzyme in general  (EB09010D)

Reference (38)：

• WATERMAN, M. R. Regulation of synthesis and activity of cytochrome P450 enzymes in physiological pathways in Cytochrome P450. Structure, Mechanism and Biochemistry. 1986, 345-386
• CAPDEVILA, J. H. Cytochrome P450 and the metabolism of arachidonic acid and oxygenated eicosanoids in Cytochrome P450. Structure, Mechanism and Biochemsitry, 2nd edition. 1995, 443-472
• SONO, M. Heme-containing oxygenases. Chem. Rev. 1996, 96, 2841-2887
• POULOS, T. L. Crystal structure of substrate-free Pseudomonas putida cytochrome P450. Biochemistry. 1986, 25, 5314-5322
• POULOS, T. L. High-resolution crystal structure of cytochrome P450cam. J. Mol. Biol. 1987, 195, 687-700

Terms in the title (4)： 変異体 ,  X線 ,  結晶構造 ,  触媒特性