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J-GLOBAL ID：200902137909692854   Reference number：97A0522781

Sphingosine l-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum.

血小板に多量に蓄積されている生理活性スフィンゴ脂質であるスフィンゴシン1りん酸は,ヒト血しょうと血清の正常な構成成分である

Author (9)： YATOMI Y (Yamanashi Medical Univ., Yamanashi) ,  IGARASHI Y (Fred Hutchinson Cancer Res. Center, WA, USA) ,  YANG L (Yamanashi Medical Univ., Yamanashi) ,  HISANO N (Yamanashi Medical Univ., Yamanashi) ,  QI R (Yamanashi Medical Univ., Yamanashi) ,  ASAZUMA N (Yamanashi Medical Univ., Yamanashi) ,  SATOH K (Yamanashi Medical Univ., Yamanashi) ,  OZAKI Y (Yamanashi Medical Univ., Yamanashi) ,  KUME S (Yamanashi Medical Univ., Yamanashi)
Material： Journal of Biochemistry  (J Biochem)
Volume： 121  Issue： 5  Page： 969-973  Publication year： May. 1997 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： sphingosine

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JST classification (1)： Fibrinolysis and blood coagulation  (EJ03040S)

Reference (34)：

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• SPIEGEL, S. Sphingolipid metabolites: members of a new class of lipid second messengers. J. Membr. Biol. 1995, 146, 225-237
• van VELDHOVEN, P. P. Subcellular localization and membrane topology of sphingosine-1-phosphate lyase in rat liver. J. Biol. Chem. 1991, 266, 12502-12507
• ZHANG, H. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 1991, 114, 155-167
• OLIVERA, A. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature. 1993, 365, 557-560

Terms in the title (9)： 血小板 ,  蓄積 ,  生理活性 ,  スフィンゴ脂質 ,  スフィンゴシン1りん酸 ,  ヒト ,  血しょう ,  血清 ,  構成成分