Art

J-GLOBAL ID：200902139164748693   Reference number：00A0667604

The First Total Synthesis of (-)-Tamandarin A.

(-)-タマンダリンAの初全合成

Author (5)： LIANG B (Univ. Pennsylvania, Pennsylvania) ,  PORTONOVO P (Univ. Pennsylvania, Pennsylvania) ,  VERA M D (Univ. Pennsylvania, Pennsylvania) ,  XIAO D (Univ. Pennsylvania, Pennsylvania) ,  JOULLIE M M (Univ. Pennsylvania, Pennsylvania)
Material： Organic Letters  (Org Lett)
Volume： 1  Issue： 8  Page： 1319-1322  Publication year： Oct. 21, 1999 
JST Material Number： W1171A  ISSN： 1523-7060  CODEN： ORLEF7  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *depsipeptide ,...

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JST classification (2)： Peptides  (CF10080G) ,  Synthesis of drugs  (GV01030F)

Substance index (19)： Tamandarin A ,  L-Lac-L-Pro-N-Methyl-D-Leu-OH ,  Z-L-Leu-L-Pro-N,O-Dimethyl-L-Tyr-N-Boc-L-Thr*-[2-(trimethylsilyl)ethoxymethyl]OH ,  [(3S,4R)-N-Cbz-3-(Triisopropylsiloxy)-4-[(S)-sec-butyl]-γAbu-]-L-Hmb-OH ,  D-Alloisoleucine ,  N-(Benzyloxycarbonyl)-D-alloisoleucine ,  (2R,3S)-2-(Benzyloxycarbonylamino)-3-methylvaleric acid pentafluorophenyl ester ,  (4R,5S)-3-Oxo-4-(benzyloxycarbonylamino)-5-methylheptanoic acid methyl ester ,  (3S,4R,5S)-3-Hydroxy-4-(benzyloxycarbonylamino)-5-methylheptanoic acid methyl ester ,  (3S,4R,5S)-3-(Triisopropylsiloxy)-4-(benzyloxycarbonylamino)-5-methylheptanoic acid methyl ester ,  (3S,4R,5S)-3-(Triisopropylsiloxy)-4-(benzyloxycarbonylamino)-5-methylheptanoic acid ,  Valine ,  (S)-2-Hydroxy-3-methylbutyric acid ,  (S)-2-Hydroxyisovaleric acid allyl ester ,  [(3S,4R)-N-Cbz-3-(Triisopropylsiloxy)-4-[(S)-sec-butyl]-γAbu-]-L-Hmb-allyl OH ,  [(3S,4R)-N-Cbz-3-(Triisopropylsiloxy)-4-[(S)-sec-butyl]-γAbu-]-L-Hmb-(pentafluorophenyl)OH ,  L-Leu-L-Pro-N,O-Dimethyl-L-Tyr-Boc-L-Thr*-[2-(trimethylsilyl)ethoxymethyl]OH ,  [(3S,4R)-3-(Triisopropylsiloxy)-4-[(S)-sec-butyl]-γAbu-]-L-Hmb-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-Boc-L-Thr*-[2-(trimethylsilyl)ethoxymethyl]OH ,  N-Boc-Cyclo[L-Thr*-[(3S,4R)-3-(triisopropylsiloxy)-4-[(S)-1-methylpropyl]-γAbu-]-L-Hmb-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-]

Terms in the title (2)： タマンダリンA ,  全合成