Art

J-GLOBAL ID：200902139359230591   Reference number：01A0285923

Inhibition of Alpha-glucosidase and Amylase by Luteolin, a Flavonoid.

フラボノイド、ルテオリンによるアルファ-グルコシダーゼとアミラーゼの阻害

Author (3)： KIM J-S (Kyungpook National Univ., Taegu, KOR) ,  KWON C-S (Andong National Univ., Andong, KOR) ,  SON K H (Andong National Univ., Andong, KOR)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 64  Issue： 11  Page： 2458-2461  Publication year： Nov. 23, 2000 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibition ,...
Semi thesaurus term： glycoside hydrolase

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JST classification (2)： Condensed derivatives of pyrane  (CF07093I) ,  Enzyme in general  (EB09010D)

Substance index (5)： Acarbose ,  Luteolin ,  Amentoflavone ,  Luteolin 7-glucoside ,  Daidzein

Reference (18)：

• 1) Mooradian, A. D. and Thurman, J. E., Drug therapy of postprandial hyperglycemia. Drugs, 57, 19-29 (1999).
• 2) Watanabe, J., Kawabata, J., Kurihara, H., and Niki, R., Isolation and identification of alpha-glucosidase inhibitors from Tochu-cha (Eucommia ulmoides). Biosci. Biotechnol. Biochem., 61, 177-178 (1997).
• 3) Kazaz, M. A., Desseaux, V., Marchis-Mouren, G., Prodanov, E., and Santimone, M., The mechanism of porcine pancreatic alpha-amylase inhibition of maltopentaose hydrolysis by acarbose, maltose and maltotriose. Eur. J. Biochem., 252, 100-107 (1998).
• 4) Uchida, R., Nasu, A., Tokutake, S., Kasai, K., Tobe, K., and Yamaji, N., Synthesis of new N-containing maltooligosaccharides, alpha-amylase inhibitors, and their biological activities. Chem. Pharm. Bull., 47, 187-193 (1999).
• 5) Havsteen, B., Flavonoids, a class of natural products of high pharmacological potency. Biochem. Pharmacol., 32, 1141-1148 (1983).

Terms in the title (5)： フラボノイド ,  ルテオリン ,  アルファ-グルコシダーゼ ,  アミラーゼ ,  阻害