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J-GLOBAL ID：200902140422169073   Reference number：96A0668988

Conserved Histidine Residues of RCC1 Are Essential for Nucleotide Exchange on Ran.

RCC1の保存ヒスチジン残基はRan上でのヌクレオチド交換に必須である

Author (9)： AZUMA Y (Kyushu Univ., Fukuoka) ,  SEINO H (Kyushu Univ., Fukuoka) ,  SEKI T (Kyushu Univ., Fukuoka) ,  UZAWA S (Kyushu Univ., Fukuoka) ,  KLEBE C (Max-Planck-Inst. Molekulare Physiologie, Dortmund, DEU) ,  OHBA T (Kyushu Univ., Fukuoka) ,  WITTINGHOFER A (Max-Planck-Inst. Molekulare Physiologie, Dortmund, DEU) ,  HAYASHI N (Kyushu Univ., Fukuoka) ,  NISHIMOTO T (Kyushu Univ., Fukuoka)
Material： Journal of Biochemistry  (J Biochem)
Volume： 120  Issue： 1  Page： 82-91  Publication year： Jul. 1996 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： DNA binding protein ,...
Semi thesaurus term： Ran ,...

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JST classification (1)： Biological function  (EB03040U)

Substance index (1)： 2′-O,3′-O-Bis[2-(methylamino)benzoyl]guanosine-5′-diphosphoric acid

Reference (33)：

• 1. Ohtsubo, M., Kai, R., Furuno, N., Sekiguchi, T., Sekiguchi, M., Hayashida, H., Kuma, K., Miyata, T., Fukushige, S., Murotsu, T., Matsubara, K., and Nishimoto, T. (1987) Isolation and characterization of the active cDNA of the human cell cycle gene (RCCI) involved in the regulation of onset of chromosome condensation. Genes Dev. 1, 585-593
• 2. Ohtsubo, M., Ozaki, H., and Nishimoto, T. (1989) The RCCI protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J. Cell Biol. 109, 1389-1397
• 3. Kai, R., Ohtsubo, M., Sekiguchi, M., and Nishimoto, T. (1986) Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation. Mot. Cell. Biol. 6, 2027-2032
• 4. Uchida, S., Sekiguchi, T., Nishitani, H., Miyauchi, K., Ohtsubo, M., and Nishimoto, T. (1990) Premature chromosome condensation is induced by a point mutation in the hamster RCCI gene. Mot. Cell. Biol. 10, 577-584
• 5. Nishitani, H., Ohtsubo, M., Yamashita, K., Iida, H., Pines, J., Yasuda, H., Shibata, Y., Hunter, T., and Nishimoto, T. (1991) Loss of RCC 1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc 2 protein kinase and mitosis. EMBO J. 10, 1555-1564

Terms in the title (4)： 保存 ,  ヒスチジン残基 ,  Ran ,  ヌクレオチド