L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase Activity.

SHEARMAN M S; BEHER D; CLARKE E E; LEWIS H D; HARRISON T; HUNT P; NADIN A; SMITH A L; CASTRO J L

Art

J-GLOBAL ID：200902142700456596 Reference number：00A0979101

L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase Activity.

L-685,458,アスパラギン酸プロテアーゼ遷移状態模倣は,アミロイドβ-蛋白質前駆体γ-セクレターゼ活性の強力な阻害剤である

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Material：
Volume： 39 Issue： 30 Page： 8698-8704 Publication year： Aug. 01, 2000
JST Material Number： B0270B ISSN： 0006-2960 CODEN： BICHAW Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Basic research of other drugs acting on central nervous system , Enzyme in general

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