Art

J-GLOBAL ID：200902143136690091   Reference number：98A0605181

Cyanocysteine-Mediated Molecular Dissection of Dihydrofolate Reductase: Occurrence of Intra- and Inter-Molecular Reactions Forming a Peptide Bond.

ジヒドロ葉酸レダクターゼのシアノシステイン介入分子切開 ペプチド結合を形成する分子内及び分子間反応の存在

Author (4)： TAKENAWA T (National Inst. Biosci. and Human Technol., Ibaraki) ,  ODA Y (Eisai Co., Ltd., Ibaraki) ,  ISHIHAMA Y (Eisai Co., Ltd., Ibaraki) ,  IWAKURA M (National Inst. Biosci. and Human Technol., Ibaraki)
Material： Journal of Biochemistry  (J Biochem)
Volume： 123  Issue： 6  Page： 1137-1144  Publication year： Jun. 1998 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *dihydrofolate reductase ,...
Semi thesaurus term： シアノシステイン ,...

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JST classification (1)： Enzyme in general  (EB09010D)

Reference (30)：

• RIZO, J. Constrained peptides: models of bioactive peptides and protein substructures. Annu. Rev. Biochem. 1992, 61, 387-418
• CATSIMPOOLAS, N. Specific cleavage of cysteine peptides by cyanide. J. Biol. Chem. 1966, 241, 1790-1796
• JACOBSON, G. R. Specific chemical cleavage in high yield at the amino peptide bonds of cysteine and cysteine residues. J. Biol. Chem. 1973, 248, 6583-6591
• DEGANI, Y. Selective cyanidation of sulfhydryl groups. II. On the synthesis of 2-nitro-5-thiocyanatobenzoic acid. J. Org. Chem. 1971, 36, 2727-2728
• DEGANI, Y. Cyanylation of sulfhydryl groups by 2-nitro-5-thiocyanobenzoic acid. High-yield modification and cleavage of peptides at cysteine residues. Biochemistry. 1974, 13, 1-11

Terms in the title (4)： ジヒドロ葉酸レダクターゼ ,  分子 ,  切開 ,  ペプチド結合