Art

J-GLOBAL ID：200902145504404552   Reference number：00A0603730

Effects of Nitric Oxide Scavenger, Carboxy-PTIO on Endotoxin-Induced Alterations in Systemic Hemodynamics in Rats.

ラット全身血液動態におけるエンドトキシン誘発変化に対する一酸化窒素スカベンジャー,カルボキシPTIOの作用

Author (8)： MIURA K (Osaka City Univ. Medical School, Osaka, JPN) ,  YAMANAKA S (Osaka City Univ. Medical School, Osaka, JPN) ,  EBARA T (Osaka City Univ. Medical School, Osaka, JPN) ,  OKUMURA M (Osaka City General Hospital, Osaka, JPN) ,  IMANISHI M (Osaka City General Hospital, Osaka, JPN) ,  KIM S (Osaka City Univ. Medical School, Osaka, JPN) ,  NAKATANI T (Osaka City Univ. Medical School, Osaka, JPN) ,  IWAO H (Osaka City Univ. Medical School, Osaka, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 82  Issue： 3  Page： 261-264  Publication year： Mar. 01, 2000 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Rattus ,...
Semi thesaurus term： endotoxin

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JST classification (2)： Drugs acting on circulatory system in general  (GW07010C) ,  Infectious diseases,parasitics diseases in general.  (GD01010H)

Substance index (1)： Carboxy PTIO

Reference (15)：

• 1 Szabo C: Alterations in nitric oxide production in various forms of circulatory shock. New Horiz 3, 2-32 (1995)
• 2 Mulder MF, van Lambalgen AA, Huisman E, Visser JJ, van den Bos GC and Thijs LG: Protective role of NO in the regional hemodynamic changes during acute endotoxemia in rats. Am J Physiol 266, H1558-H1564 (1994)
• 3 Fishman D, Liaudet L, Lazor R, Perret CH and Feihl F: L Canavanine, an inhibitor of inducible nitric oxide synthase, improves venous return in endotoxemic rats. Crit Care Med 25, 469-475 (1997)
• 4 MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, Stevens K, Xie QW, Sokol K, Hutchinson N, Chen H and Mudgett JS: Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide. Cell 81, 641-650 (1995)
• 5 Yoshida M, Akaike T, Wada Y, Sato K, Ikeda K, Ueda S and Maeda H: Therapeutic effects of imidazolineoxyl N-oxide against endotoxin shock through its direct nitric oxide-scavenging activity. Biochem Biophys Res Commun 202, 923-930 (1994)

Terms in the title (8)： ラット ,  全身 ,  血液動態 ,  エンドトキシン ,  誘発 ,  一酸化窒素 ,  スカベンジャー ,  カルボキシPTIO