Art

J-GLOBAL ID：200902146968270377   Reference number：98A0048890

Betidamino Acid Scan of the GnRH Antagonist Acyline.

GnRHきっ抗薬アシリンのベチドアミノ酸構造への変換

Author (9)： JIANG G (Ferring Res. Inst. Inc., California) ,  MILLER C (Salk Inst. Biological Studies, California) ,  PORTER J (Alanex Corp., California) ,  CRAIG A G (Salk Inst. Biological Studies, California) ,  KRAFT P (R.W. Johnson Pharmaceutical Res. Inst., New Jersey) ,  BURRIS T P (R.W. Johnson Pharmaceutical Res. Inst., New Jersey) ,  CAMPEN C A (R.W. Johnson Pharmaceutical Res. Inst., New Jersey) ,  RIVIER C L (Salk Inst. Biological Studies, California) ,  RIVIER J E (Salk Inst. Biological Studies, California)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 40  Issue： 23  Page： 3739-3748  Publication year： Nov. 07, 1997 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： polypeptide ,...
Semi thesaurus term： LH-RH ,...

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JST classification (2)： Basic research of drugs acting on endocrine system and reproductive organ  (GW10010K) ,  Peptides  (CF10080G)

Substance index (14)： Acyline ,  [Ac-L-βNal¹]acyline ,  [Ac-D-Agl(2-naphthoyl)¹]acyline ,  [Ac-L-Agl(2-naphthoyl)¹]acyline ,  [Ac-D-Agl(Me,2-naphthoyl)¹]acyline ,  [Ac-L-Agl(Me,2-naphthoyl)¹]acyline ,  [D-Agl(4-Cl-benzoyl)²]acyline ,  [L-Agl(4-Cl-benzoyl)²]acyline ,  [D-Agl(Me,4-Cl-benzoyl)²]acyline ,  [L-Agl(Me,4-Cl-benzoyl)²]acyline ,  [D-Agl(Pca)²]acyline ,  [L-Agl(Pca)²]acyline ,  [D-Agl(Apc)²]acyline ,  [L-Agl(Apc)²]acyline

Terms in the title (4)： GnRH ,  きっ抗薬 ,  アシリン ,  酸