Art

J-GLOBAL ID：200902147875851767   Reference number：02A0333186

Thiophene Derivatives: A New Series of Potent Norepinephrine and Serotonin Reuptake Inhibitors.

チオフェン誘導体 新しい一連の強力なノルエピネフリン及びセロトニン再取込み阻害剤

Author (6)： ZHANG A (Georgetown Univ. Medical Center, DC, USA) ,  ZHOU G (Georgetown Univ. Medical Center, DC, USA) ,  RONG S-B (Georgetown Univ. Medical Center, DC, USA) ,  JOHNSON K M (Univ. Texas, TX, USA) ,  ZHANG M (Univ. Texas, TX, USA) ,  KOZIKOWSKI A P (Georgetown Univ. Medical Center, DC, USA)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 12  Issue： 7  Page： 993-995  Publication year： Apr. 08, 2002 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,...
Semi thesaurus term： bridged compound ,...

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JST classification (2)： Other condensed derivatives of pyridine  (CF07097Y) ,  Synthesis of drugs  (GV01030F)

Substance index (21)： Benzoic acid [(1S,3S,6R,10S)-9-[(Z)-(4-iodophenyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl ester ,  Benzoic acid [(1S,3S,6R,10S)-9-[(Z)-(3-chloro-4-iodophenyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl ester ,  (1S,3S,6R,10S)-9-[(Z)-(Tributylstannyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid methyl ester ,  2-Iodothiophene ,  2-Methyl-5-iodothiophene ,  2,5-Diiodothiophene ,  (1S,3S,6R,10S)-9-[(Z)-(2-Thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid methyl ester ,  (1S,3S,6R,10S)-9-[(Z)-(5-Methyl-2-thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid methyl ester ,  (1S,3S,6R,10S)-9-[(Z)-(5-Iodo-2-thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid methyl ester ,  (1S,3S,6R,10S)-9-[(Z)-(2-Thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid chloride ,  (1S,3S,6R,10S)-9-[(Z)-(2-Thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid isopropyl ester ,  (1S,3S,6R,10S)-9-[(Z)-(2-Thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-methanol ,  Acetic acid [(1S,3S,6R,10S)-9-[(Z)-(2-thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl ester ,  Pivalic acid [(1S,3S,6R,10S)-9-[(Z)-(2-thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl ester ,  Benzoic acid [(1S,3S,6R,10S)-9-[(Z)-(2-thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl ester ,  2-Naphthalenecarboxylic acid [(1S,3S,6R,10S)-9-[(Z)-(2-thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl ester ,  N-[[(1S,3S,6R,10S)-9-[(Z)-(2-Thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl]acetamide ,  N-[[(1S,3S,6R,10S)-9-[(Z)-(2-Thienyl)methylene]-7-azatricyclo[4.3.1.0^3,7]decane-10-yl]methyl]carbamic acid tert-butyl ester ,  Dopamine ,  Serotonin ,  Norepinephrine

Terms in the title (3)： チオフェン誘導体 ,  ノルエピネフリン ,  セロトニン再取込み阻害剤