Art

J-GLOBAL ID：200902149997652415   Reference number：01A0226299

Vaccination Effect of Interleukin-6-producing Pancreatic Cancer Cells in Nude Mice. A Model of Tumor Prevention and Treatment in Immune-compromised Patients.

ヌードマウスにおけるインターロイキン-6産生性すい臓腫よう細胞のワクチン効果 免疫不全患者における腫よう防御と治療のモデル

Author (7)： YANO T (Hokkaido Univ. School of Medicine, Sapporo) ,  ISHIKURA H (Hokkaido Univ. School of Medicine, Sapporo) ,  KATO HIROA (Hokkaido Univ. School of Medicine, Sapporo) ,  OGAWA Y (Hokkaido Univ. School of Medicine, Sapporo) ,  KONDO S (Hokkaido Univ. School of Medicine, Sapporo) ,  KATO HIROY (Hokkaido Univ. School of Medicine, Sapporo) ,  YOSHIKI T (Hokkaido Univ. School of Medicine, Sapporo)
Material： Japanese Journal of Cancer Research  (Proceedings. Annual Meeting of the Japanese Cancer Association)
Volume： 92  Issue： 1  Page： 83-87  Publication year： Jan. 31, 2001 
JST Material Number： F0633A  ISSN： 0910-5050  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *pancreatic tumor ,...

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JST classification (2)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (15)：

• KAWANO, M. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myeloma. Nature. 1988, 332, 83-85
• OMI, M. Interleukin (IL)-6 as a pancreas carcinoma-derived vascular permeability regulator in vitro. Pathol. Res. Pract. 1996, 192, 1107-1112
• SAITO, K. Interleukin-6 produced by pancreatic carcinoma cells enhances humoral immune responses against tumor cells: a possible event in tumor regression. Int. J. Cancer. 1998, 75, 284-289
• INOUE, K. The role of interleukin-6 in inhibition of lung metastasis in subcutaneous tumor-bearing mice. Oncol. Rep. 2000, 7, 69-73
• PORGADOR, A. Immunotherapy via gene therapy: comparison of the effects of tumor cells transduced with the interleukin-2, interleukin-6 or interferon-γ genes. J. Immunother. 1993, 14, 191-201

Terms in the title (10)： ヌードマウス ,  インターロイキン-6 ,  すい臓腫よう ,  細胞 ,  ワクチン効果 ,  免疫不全患者 ,  腫よう ,  防御 ,  治療 ,  モデル