Art

J-GLOBAL ID：200902151038752448   Reference number：00A0089195

Two Possible Pathways for Acquisition of Mutations Related to Nelfinavir Resistance.

ネルフィナビル耐性に関連する変異獲得の二つの可能性ある経路

Author (9)： SUGIURA W (National Inst. Infectious Diseases, Tokyo) ,  YAMADA K (St. Marianna Univ. School of Medicine, Kanagawa) ,  ISHIKAWA M (Tohoku Univ. School of Medicine, Miyagi) ,  MIURA T (Haga Red Cross Hospital, Tochigi) ,  FUKUTAKE K (Tokyo Medical Univ., Tokyo) ,  GOUCHI K (Teikyo Univ. School of Medicine, Tokyo) ,  AJISAWA A (Tokyo Metropolitan Komagome Hospital, Tokyo) ,  IWAMOTO A (Univ. Tokyo, Tokyo) ,  NAGAI Y (National Inst. Infectious Diseases, Tokyo)
Material： Japanese Journal of Infectious Diseases  (日本感染症雑誌)
Volume： 52  Issue： 4  Page： 175-176  Publication year： Aug. 1999 
JST Material Number： F0552A  ISSN： 1344-6304  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *anti-AIDS agent ,...
Semi thesaurus term： acquired immunodeficiency syndrome

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JST classification (1)： Clinical application of antiviral drugs  (GW17050Z)

Substance index (3)： Ritonavir ,  Indinavir ,  Nelfinavir

Reference (3)：

• 1. Hirsch, M.S., Conway, B., D'Aquila, R.T., Johnson, V.A., Brun-Vezinet, F., Clotet, B., Demeter, L.M., Hammer, S. M., Jacobsen, D.M., Kuritzkes, D. R., Loveday, C., Mellors, J. W., Vella, S. and Richman, D.D. (1998): Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society - USA Panel. JAMA, 279, 1984-1991.
• 2. Patick, A.K., Duran, M., Cao, Y., Shugarts, D., Keller, M.R., Mazabel, E., Knowles, M., Chapman, S., Kuritzkes, D.R. and Markowitz, M. (1998): Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir. Antimicrob. Agents Chemother., 42, 2637-2644.
• 3. Sugiura, W., Matsuda, M., Matsuda, Z., Abumi, H., Okano, A., Oishi, T., Moriya, K., Yamamoto, Y., Fukutake, K., Mimaya, J., Ajisawa, A., Taki, M., Yamada, K. and Nagai, Y. (1999): Identification of insertion mutations in HIV-1 reverse transcriptase causing multiple drug resistance to nucleoside analogue reverse transcriptase inhibitors. J. Hum. Virol., 12,146-153.

Terms in the title (6)： ネルフィナビル ,  耐性 ,  変異 ,  獲得 ,  可能性 ,  経路