The Possible Involvement of GABA<sub>A</sub> Systems in the Antinarcotic Effect of Majonoside-R2, a Major Constituent of Vietnamese Ginseng, in Mice.

HUONG N T T; MATSUMOTO K; YAMASAKI K; DUC N M; NHAM N T; WATANABE H

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J-GLOBAL ID：200902153549056540 Reference number：96A0868069

The Possible Involvement of GABA_A Systems in the Antinarcotic Effect of Majonoside-R2, a Major Constituent of Vietnamese Ginseng, in Mice.

マウスにおいて,ベトナム産ニンジンの主成分であるマジョノシド-R2の麻薬きっ抗作用にGABA_A系が関与している可能性

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Author (6)： , , , , ,
Material：
Volume： 71 Issue： 4 Page： 345-349 Publication year： Aug. 1996
JST Material Number： G0813A ISSN： 0021-5198 CODEN： JJPAA Document type： Article
Article type：短報 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Basic research of pharmacology of crude drugs

Reference (13)：

1) Duc NM, Kasai R, Ohtani K, Ito A, Nham NT, Yamasaki K and Tanaka 0: Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I. Chem Pharm Bull (Tokyo) 41, 2010-2014 (1993)
2) Huong NTT, Matsumoto K, Yamasaki K, Duc NM, Nham NT and Watanabe H: Effects of majonoside-R2 on pentobarbital sleep and gastric lesion in psychologically stressed mice. Pharmacol Biochem Behav 53, 957-963 (1996)
3) Huong NTT, Matsumoto K, Yamasaki K, Duc NM, Nham NT and Watanabe H: Effects of Vietnamese ginseng on opioid agonist and conditioned fear stress-induced antinociception. Phyto Med 3, 33-39 (1996)
4) Takagi H, Inukai T and Nakama M: A modification of Haffner''s method for testing analgesics. Jpn J Pharmacol 16, 287-294 (1966)
5) Dewey WL, Harris LS, Howes JF and Nuite JA: The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests. J Pharmacol Exp Ther 175, 435-442 (1970)

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The Possible Involvement of GABAA Systems in the Antinarcotic Effect of Majonoside-R2, a Major Constituent of Vietnamese Ginseng, in Mice.

The Possible Involvement of GABA_A Systems in the Antinarcotic Effect of Majonoside-R2, a Major Constituent of Vietnamese Ginseng, in Mice.