Art

J-GLOBAL ID：200902153614720231   Reference number：02A0065840

Domino Michael-O-alkylation reaction: one-pot synthesis of 2,4-diacylhydrofuran derivatives and its application to antitumor naphthofuran synthesis.

ドミノMichael-O-アルキル化反応 2,4-ジアシルヒドロフラン誘導体のワンポット合成および抗腫よう性ナフトフラン合成への適用

Author (6)： HAGIWARA H (Niigata Univ., Niigata, JPN) ,  SATO K (Niigata Univ., Niigata, JPN) ,  NISHINO D (Niigata Univ., Niigata, JPN) ,  HOSHI T (Niigata Univ., Niigata, JPN) ,  SUZUKI T (Niigata Univ., Niigata, JPN) ,  ANDO M (Niigata Univ., Niigata, JPN)
Material： Journal of the Chemical Society. Perkin Transactions. 1  (Perkin Transactions 1)
Issue： 22  Page： 2946-2957  Publication year： Nov. 21, 2001 
JST Material Number： A0499B  ISSN： 1472-7781  CODEN： JCPRB4  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： one-pot synthesis ,...
Semi thesaurus term： ドミノ反応

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JST classification (2)： Furans  (CF07072V) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (39)： BBI-608 ,  2,3,4,5-Tetrahydro-3aH-cyclopenta[b]furan-2,3a-dicarboxylic acid 2-methyl 3a-ethyl ester ,  2,3,3a,4,5,6-Hexahydrobenzofuran-2,3a-dicarboxylic acid dimethyl ester ,  2,3,4,5,6,7-Hexahydro-4-oxobenzofuran-2-carboxylic acid methyl ester ,  3a-Methyl-4-oxo-2,3,3a,4,5,6-hexahydrobenzofuran-2-carboxylic acid methyl ester ,  4-Oxo-6-methyl-2,3-dihydro-4H-furo[3,2-c]pyran-2-carboxylic acid methyl ester ,  1-Methylene-6-oxo-2,7-dioxaspiro[4.4]nonane-3-carboxylic acid methyl ester ,  7-(Phenylsulfinyl)-2,3,3a,4,5,6-hexahydrobenzofuran-2-carboxylic acid methyl ester ,  7-Oxo-2,3,4,5,6,7-hexahydrobenzofuran-2-carboxylic acid methyl ester ,  5-Methyl-2,3-dihydrofuran-2,4-dicarboxylic acid dimethyl ester ,  4-Acetyl-5-methyl-2,3-dihydrofuran-2-carboxylic acid methyl ester ,  4-Methyl-5-methylenetetrahydrofuran-2,4-dicarboxylic acid 2-methyl 4-ethyl ester ,  3,5-Dimethyl-2,3-dihydrofuran-2,4-dicarboxylic acid dimethyl ester ,  3,5-Dimethyl-4-acetyl-2,3-dihydrofuran-2-carboxylic acid methyl ester ,  3-Methyl-2,3,4,5-tetrahydro-3aH-cyclopenta[b]furan-2,3a-dicarboxylic acid 2-methyl 3a-ethyl ester ,  2-Acetyl-2,3,4,5-tetrahydro-3aH-cyclopenta[b]furan-3a-carboxylic acid ethyl ester ,  2-Acetyl-2,3,5,6-tetrahydrobenzofuran-3a(4H)-carboxylic acid methyl ester ,  2-Acetyl-2,3,6,7-tetrahydrobenzofuran-4(5H)-one ,  2-Acetyl-3a-methyl-3,3a,5,6-tetrahydrobenzofuran-4(2H)-one ,  2-Acetyl-6-methyl-2,3-dihydro-4H-furo[3,2-c]pyran-4-one ,  2-Methyl-5-acetyl-4,5-dihydrofuran-3-carboxylic acid methyl ester ,  2-Methyl-5-acetyl-4,5-dihydrofuran-3-carboxylic acid ethyl ester ,  2-Methyl-5-acetyl-4,5-dihydrofuran-3-carboxylic acid tert-butyl ester ,  2-Methyl-3,5-diacetyl-4,5-dihydrofuran ,  2-Methyl-3-acetyl-3aα,5,6,7aβ-tetrahydrobenzofuran-7(4H)-one ,  2-Methyl-3-acetyl-5,6-dihydrobenzofuran-7(4H)-one ,  2-Methyl-7-oxo-3aα,4,5,6,7,7aβ-hexahydrobenzofuran-3-carboxylic acid methyl ester ,  3,4,5aα,8,9,9aβ-Hexahydrodibenzofuran-1,6(2H,7H)-dione ,  3-Methyl-7,8,9,9aβ-tetrahydro-1H-pyrano[4,3-b]benzofuran-1,6(5aαH)-dione ,  2-Acetyl-6,7-dihydrobenzofuran-4(5H)-one ,  2-Methyl-5-acetylfuran-3-carboxylic acid ethyl ester ,  2-Methyl-3,5-diacetylfuran ,  2-Acetyl-2,3-dihydronaphtho[2,3-b]furan-4,9-dione ,  2-Methyl-5-acetylfuran-3-carboxylic acid methyl ester ,  2-Acetyl-6-methyl-4H-furo[3,2-c]pyran-4-one ,  4-Acetyl-5-methylfuran-2-carboxylic acid methyl ester ,  4-Oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid methyl ester ,  Dehydroiso-α-lapachone ,  2-(1-Hydroxyethyl)naphtho[2,3-b]furan-4,9-dione

Terms in the title (4)： アルキル化反応 ,  誘導体 ,  ワンポット合成 ,  抗腫よう性