Art

J-GLOBAL ID：200902154301925513   Reference number：02A0956088

Trifluoromethyl Ketones as Inhibitors of Histone Deacetylase.

ヒストンデアセチラーゼ阻害剤としてのトリフルオロメチルケトン類

Author (9)： FREY R R (Abbott Lab., IL, USA) ,  WADA C K (Abbott Lab., IL, USA) ,  GARLAND R B (Abbott Lab., IL, USA) ,  CURTIN M L (Abbott Lab., IL, USA) ,  MICHAELIDES M R (Abbott Lab., IL, USA) ,  LI J (Abbott Lab., IL, USA) ,  PEASE L J (Abbott Lab., IL, USA) ,  GLASER K B (Abbott Lab., IL, USA) ,  DAVIDSEN S K (Abbott Lab., IL, USA)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 12  Issue： 23  Page： 3443-3447  Publication year： Dec. 02, 2002 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *aliphatic ketone ,...
Semi thesaurus term： HT1080 cell

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JST classification (2)： Aliphatic ketones  (CF03190Q) ,  Synthesis of drugs  (GV01030F)

Substance index (30)： SAHA ,  Trapoxin B ,  MS-275 ,  7-(4′-Cyano-4-biphenylyloxy)heptanehydroximic acid ,  Biphenyl-4-ol ,  7-Bromoheptanoic acid methyl ester ,  Octanedioic acid 1-methyl ester ,  5-Hexyn-1-ol ,  1,1,1-Trifluoro-7-(4-biphenylyloxy)-2-heptanone ,  1,1,1-Trifluoro-8-(4-biphenylyloxy)-2-octanone ,  1,1,1-Trifluoro-9-(4-biphenylyloxy)-2-nonanone ,  1,1,1-Trifluoro-8-(4-biphenylyloxy)-3-octyne-2-one ,  (3E)-1,1,1-Trifluoro-8-(4-biphenylyloxy)-3-octene-2-one ,  1-[(1R)-2α-[4-(4-Biphenylyloxy)butyl]cyclopropane-1β-yl]-2,2,2-trifluoroethanone ,  3-[4-(4-Biphenylyloxy)butoxy]-1,1,1-trifluoro-2-propanone ,  3-[4-(4-Biphenylyloxy)butylthio]-1,1,1-trifluoro-2-propanone ,  1,1,1-Trifluoro-8-phenoxy-2-octanone ,  1,1,1-Trifluoro-8-(3-biphenylyloxy)-2-octanone ,  1,1,1-Trifluoro-8-(4-phenoxyphenoxy)-2-octanone ,  8-(4-Biphenylyloxy)-2-octanone ,  SATFMK ,  N-(4-Biphenylyl)-8-oxo-9,9,9-trifluorononanamide ,  N-(3-Biphenylyl)-8-oxo-9,9,9-trifluorononanamide ,  N-(2-Biphenylyl)-8-oxo-9,9,9-trifluorononanamide ,  N-(4-Phenoxyphenyl)-8-oxo-9,9,9-trifluorononanamide ,  N-(3-Phenoxyphenyl)-8-oxo-9,9,9-trifluorononanamide ,  N-(4-Phenyl-2-thiazolyl)-8-oxo-9,9,9-trifluorononanamide ,  N-Phenyl-4-(trifluoroacetyl)benzenepropionamide ,  N-Phenyl[4-[(1E)-3-oxo-4,4,4-trifluoro-1-butenyl]phenoxy]acetamide ,  N-(3-Biphenylyl)-8-hydroxy-9,9,9-trifluorononanamide

Terms in the title (2)： ヒストンデアセチラーゼ阻害剤 ,  トリフルオロメチルケトン