Art

J-GLOBAL ID：200902154333484772   Reference number：00A0854171

Cytochrome P4501A1-Inhibitory Action of Antimutagenic Anthraquinones in Medicinal Plants and the Structure-activity Relationship.

中国薬草に含まれる抗変異原性アンスラキノン類のシトクロームP450阻害作用とその構造相関

Author (5)： SUN M (Kobe Univ., Kobe, JPN) ,  SAKAKIBARA H (Kobe Univ., Kobe, JPN) ,  ASHIDA H (Kobe Univ., Kobe, JPN) ,  DANNO G (Kobe Univ., Kobe, JPN) ,  KANAZAWA K (Kobe Univ., Kobe, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 64  Issue： 7  Page： 1373-1378  Publication year： Jul. 23, 2000 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： plant preparation ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=00A0854171&from=J-GLOBAL&jstjournalNo=G0021A") }}

JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Other condensed tricyclic carbocyclic compounds  (CF06080R)

Substance index (14)： Anthraquinone ,  Quinizarin ,  Alizarine ,  Danthron ,  Chrysophanol ,  Rhein ,  Emodin ,  Purpurin ,  2-Hydroxy-1,4-naphthoquinone ,  Anthracene ,  Anthrone ,  Dithranol ,  1,4-Anthraquinone ,  Anthrafravic acid

Reference (29)：

• 1) Kada, T. and Shimoi, K., Desmutagens and bio-antimutagens—Their modes of action. BioEssays, 7, 113-116 (1987).
• 2) Wakabayashi, K., Nagao, M., Esumi, H., and Sugimura, T., Food-derived mutagens and carcinogens. Cancer Res., 52, 2092s-2098s (1992).
• 3) Matsukura, N., Kawachi, T., Morino, K., Ohgaki, H., and Sugimura, T., Carcinogenicity in mice of mutagenic compounds from a tryptophan pyrolyzate. Science, 213, 346-347 (1981).
• 4) Kato, R. and Yamazoe, Y., Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates. Jpn. J. Cancer Res., 78, 297-311 (1987).
• 5) Frandsen, H., Rasmussen, E. S., Nielsen, P. A., Farmer, P., Dragsted, L., and Larsen, J. C., Metabolic formation, synthesis and genotoxicity of the N-hydroxy derivative of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP). Mutagenesis, 6, 93-98 (1990).

Terms in the title (7)： 中国 ,  薬草 ,  抗変異原性 ,  アンスラキノン類 ,  シトクロームP450 ,  阻害作用 ,  相関