Development and evaluation of peptide-based prolyl oligopeptidase inhibitors. Introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design.

GOOSSENS F; VANHOOF G; DE MEESTER I; AUGUSTYNS K; BORLOO M; TOURWE D; HAEMERS A; SCHARPE S

Art

J-GLOBAL ID：200902154635240139 Reference number：98A0053541

Development and evaluation of peptide-based prolyl oligopeptidase inhibitors. Introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design.

ペプチドに基づくプロリルオリゴペプチダーゼ阻害剤の開発と評価阻害剤設計のきっかけとしてのN-ベンジルオキシカルボニル-プロリル-3-フルオロピロリジンの紹介

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Material：
Volume： 250 Issue： 1 Page： 177-183 Publication year： Nov. 15, 1997
JST Material Number： B0206B ISSN： 0014-2956 CODEN： EJBCAI Document type： Article
Article type：原著論文 Country of issue： United Kingdom (GBR) Language： ENGLISH (EN)

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Enzyme in general , Basic research of enzyme preparations and enzyme inhibitor preparations

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