Art

J-GLOBAL ID：200902156598096246   Reference number：98A0754523

Zinc Ions Prevent Processing of Caspase-3 during Apoptosis Induced by Geranylgeraniol in HL-60 Cells.

ゲラニルゲラニオールで誘導されたHL60細胞のアポトーシスにおけるカスパーゼ3のプロセシングを亜鉛イオンは阻害する

Author (6)： AIUCHI T (Showa Univ., Tokyo) ,  MIHARA S (Showa Univ., Tokyo) ,  NAKAYA M (Showa Univ., Tokyo) ,  MASUDA Y (Showa Univ., Tokyo) ,  NAKAJO S (Showa Univ., Tokyo) ,  NAKAYA K (Showa Univ., Tokyo)
Material： Journal of Biochemistry  (J Biochem)
Volume： 124  Issue： 2  Page： 300-303  Publication year： Aug. 1998 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： HL60 cell ,...
Semi thesaurus term： geranylgeraniol ,...

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JST classification (2)： Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (1)： Geranyl geraniol

Reference (17)：

• OHIZUMI, H. Geranylgeraniol is a potent inducer of spoptosis in tumor cells. J.Biochem. 1995, 117, 11-13
• OHIZUMI, H. Induction of apoptosis in various tumor cell lines by geranylgeraniol. Anticancer Res. 1997, 17, 1051-1058
• MASUDA, Y. Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells. Int.J.Cancer. 1997, 71, 691-697
• MASUDA, Y. Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells. Biochem.Biophys.Res.Commun. 1997, 234, 641-645
• PERRY, D. K. Zinc is a potent inhibitor of the apoptotic protease,caspase-3.A novel target for zinc in the inhibition of apoptosis. J.Biol.Chem. 1997, 272, 18530-18533

Terms in the title (8)： ゲラニルゲラニオール ,  誘導 ,  HL60細胞 ,  アポトーシス ,  カスパーゼ3 ,  プロセシング ,  亜鉛イオン ,  阻害