Art

J-GLOBAL ID：200902158743925674   Reference number：00A0868105

A Three-Dimensional Model of Lanosterol 14α-Demethylase of Candida albicans and Its Interaction with Azole Antifungals.

Candida albicansのラノステロール14α-デメチラーゼの3次元モデルおよびアゾール抗真菌薬との相互作用

Author (8)： JI H (Second Military Medical Univ., Shanghai, CHN) ,  ZHANG W (Second Military Medical Univ., Shanghai, CHN) ,  ZHOU Y (Second Military Medical Univ., Shanghai, CHN) ,  ZHANG M (Second Military Medical Univ., Shanghai, CHN) ,  ZHU J (Second Military Medical Univ., Shanghai, CHN) ,  SONG Y (Second Military Medical Univ., Shanghai, CHN) ,  LUE J (Second Military Medical Univ., Shanghai, CHN) ,  ZHU J (Second Military Medical Univ., Shanghai, CHN)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 43  Issue： 13  Page： 2493-2505  Publication year： Jun. 29, 2000 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Candida albicans ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=00A0868105&from=J-GLOBAL&jstjournalNo=D0102A") }}

JST classification (1)： Basic research of antifungal drugs  (GW17060K)

Substance index (20)： Miconazole ,  Oxiconazole ,  Ketoconazole ,  Itraconazol ,  Fluconazole ,  D-0870 ,  SM-9164 ,  Ravuconazole ,  SDZ-89485 ,  TAK-187 ,  Voriconazole ,  SM-8668 ,  N-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]4-(trifluoromethyl)benzamide ,  3-[4-(Trifluoromethyl)benzoyl]-4α-methyl-5-(2,4-difluorophenyl)-5β-[(1H-1,2,4-triazole-1-yl)methyl]oxazolidine ,  1,3-Bis(1H-1,2,4-triazole-1-yl)-2-[2-(trifluoromethyl)phenyl]propane-2-ol ,  1,3-Bis(1H-1,2,4-triazole-1-yl)-2-(4-fluoro-2-methylphenyl)propane-2-ol ,  1,3-Bis(1H-1,2,4-triazole-1-yl)-2-[2-methoxy-4-(trifluoromethyl)phenyl]propane-2-ol ,  1,3-Bis(1H-1,2,4-triazole-1-yl)-2-[4-(trifluoromethyl)phenyl]propane-2-ol ,  1,3-Bis(1H-1,2,4-triazole-1-yl)-2-(4′-chloro-1,1′-biphenyl-4-yl)propane-2-ol ,  1,3-Bis(1H-1,2,4-triazole-1-yl)-2-[4-(4-chlorophenoxy)phenyl]propane-2-ol

Terms in the title (6)： Candida ,  ラノステロール ,  3次元モデル ,  アゾール ,  抗真菌薬 ,  相互作用