Art

J-GLOBAL ID：200902158890132930   Reference number：99A0074811

(±)-cis-2-Methylspiro [1,3-oxathiolane-5,3′-quinuclidine] Hydrochloride, Hemihydrate (SNI-2011, Cevimeline Hydrochloride) Induces Saliva and Tear Secretions in Rats and Mice: The Role of Muscarinic Acetylcholine Receptors.

(±)-cis-2-メチルスピロ[1,3-オキサチオラン-5,3′-キヌクリジン]塩酸塩,半水和物(SNI-2011,塩酸セビメリン)はラットおよびマウスにおいて唾液および涙液分泌を誘導する ムスカリン性アセチルコリン受容体の役割

Author (9)： IGA Y (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  ARISAWA H (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  OGANE N (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  SAITO Y (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  TOMIZUKA T (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  NAKAGAWA-YAGI Y (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  MASUNAGA H (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  YASUDA H (Snow Brand Milk Products Co., Ltd., Tochigi, JPN) ,  MIYATA N (Snow Brand Milk Products Co., Ltd., Tochigi, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 78  Issue： 3  Page： 373-380  Publication year： Nov. 1998 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *tear ,...
Semi thesaurus term： bridged compound

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JST classification (2)： Drugs acting on nervous system in general  (GW02000I) ,  Basic research of other drugs  (GW23010K)

Substance index (3)： Quinuclidinyl benzilate ,  Acetylcholine ,  Cevimeline hydrochloride

Reference (27)：

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• 5 Valdez IH, Atkinson JC, Ship JA and Fox PC: Major salivary gland function in patients with radiation-induced xerostomia: Flow rates and sialochemistry. Int J Radiat Oncol Biol Phys 25, 41 - 47 (1993)

Terms in the title (14)： CIS ,  キヌクリジン ,  塩酸塩 ,  水和物 ,  SNI-2011 ,  塩酸セビメリン ,  ラット ,  マウス ,  唾液 ,  涙液 ,  分泌 ,  誘導 ,  ムスカリン性アセチルコリン受容体 ,  役割