Art

J-GLOBAL ID：200902159541554980   Reference number：02A0493752

1α25(OH)₂D₃ interferes with retinoic acid-induced inhibition of c-fos gene expression for AP-1 formation in osteoblastic cells.

1α25(OH)₂D₃は骨芽細胞におけるAP-1生成のためのc-fos遺伝子発現のレチノイン酸誘発性阻害に干渉する

Author (4)： TAKESHITA A (Meikai Univ. School of Dentistry, Saitama) ,  YASUDA H (Meikai Univ. School of Dentistry, Saitama) ,  ISHIDA M (Meikai Univ. School of Dentistry, Saitama) ,  OCHIAI K (Meikai Univ. School of Dentistry, Saitama)
Material： Journal of Oral Science  (J Oral Sci)
Volume： 44  Issue： 1  Page： 27-34  Publication year： Mar. 2002 
JST Material Number： Z0759A  ISSN： 1343-4934  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： MC3T3-E1細胞 ,...

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JST classification (2)： Basic research of other drugs acting on metabolism  (GW13060I) ,  Gene expression  (EC02040Q)

Substance index (4)： Tretinoin ,  Calcitriol ,  24,25-Dihydroxyvitamin D3 ,  22-Oxa-1,25-dihydroxyvitamin D₃

Reference (33)：

• 1. Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Decimo, D., LeMeur, M., Dierich, A., Gorry, P. and Chambon, P. (1995) Developmental roles of the retinoic acid receptors. J. Steroid Biochem. Mol. Biol. 53,475-486
• 2. Kraemer, K.H., DiGiovanna, J. J., Moshell, A.N., Tarone, R.E. and Peck, G.L. (1988) Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin. N. Enl. J. Med. 318, 1633-1637
• 3. Brinckerhoff, C.E., Coffey, J.W. and Sullivan, A.C. (1983) Inflammation and collagenase production in rats with adjuvant arthritis reduced with 13-cisretinoic acid. Science 221,756-758
• 4. Yang-Yen, H.F., Zhang, X.K., Graupner, G., Tzukerman, M., Sakamoto, B., Karin, M. and Pfahl, M. (1991) Antagonism between retinoic acid receptors and AP-1 : implications for tumor promotion and inflammation. New Biol. 3, 1206-1219
• 5. Busam, K.J., Roberts, A.B. and Sporn, M.B. (1992) Inhibition of mitogen-induced c-fos expression in melanoma cells by retinoic acid involves the serum response element. J. Biol. Chem. 267, 19971-19977

Terms in the title (6)： 骨芽細胞 ,  AP-1 ,  c-fos遺伝子発現 ,  レチノイン酸 ,  阻害 ,  干渉