Art

J-GLOBAL ID：200902161905663130   Reference number：98A0975072

N-acetylcysteine improves cytotoxic activity of cirrhotic rat liver-associated mononuclear cells.

N-アセチルシステインは硬変ラット肝臓に関連する単核細胞の細胞傷害性を改善する

Author (9)： TSUYUKI S (Kyoto Univ., Kyoto, JPN) ,  YAMAUCHI A (Kyoto Univ., Kyoto, JPN) ,  NAKAMURA H (Kyoto Univ., Kyoto, JPN) ,  NAKAMURA Y (Kyoto Univ., Kyoto, JPN) ,  KINOSHITA K (Kyoto Univ., Kyoto, JPN) ,  GOMI T (Kyoto Univ., Kyoto, JPN) ,  KAWAI Y (Kyoto Univ., Kyoto, JPN) ,  OHMORI K (Kyoto Univ., Kyoto, JPN) ,  INAMOTO T (Kyoto Univ., Kyoto, JPN)
Material： International Immunology  (Int Immunol)
Volume： 10  Issue： 10  Page： 1501-1508  Publication year： Oct. 1998 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *NK activity ,...
Semi thesaurus term： 単核細胞 ,...

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JST classification (2)： Biophylaxis and immune systems in general  (ED01010F) ,  Experimental treatment for tumors  (GE02040Y)

Substance index (3)： Glutathione ,  Acetylcysteine ,  Buthionine sulfoximine

Reference (35)：

• HIROFUJI, H. Natural killer and activated killer activities in chronic liver disease and hepatocellular carcinoma: evidence for a decreased lymphokine-induced activity of effector cells. Clin. Exp. Immunol. 1987, 68, 348
• VENTO, S. Immunological aspects of chronic active hepatitis. Clin. Exp. Immunol. 1987, 68, 225
• SHIGESAWA, T. Significance of plasma glutathione determination in patients with alcoholic and non-alcoholic liver disease. J. Gastroenterol. Hepatol. 1992, 7, 7
• ALTOMARE, E. Hepatic glutathione content in patients with alcoholic and non alcoholic liver diseases. Life Sci. 1988, 43, 991
• YAMAUCHI, A. Requirement of thiol compounds as reducing agents for IL-2 mediated induction of LAK activity and proliferation of human NK cells. J. Immunol. 1993, 151, 5535

Terms in the title (5)： N-アセチルシステイン ,  ラット ,  肝臓 ,  単核細胞 ,  細胞傷害性