Art

J-GLOBAL ID：200902162043789211   Reference number：02A0646111

Matrix Metalloproteinase Inhibitor, Marimastat, Decreases Peritoneal Spread of Gastric Carcinoma in Nude Mice.

マトリックスメタロプロテアーゼ阻害剤,マリマスタットはヌードマウスにおける胃癌の腹腔散在を低下させる

Author (9)： KIMATA M (Keio Univ., Tokyo) ,  OTANI Y (Keio Univ., Tokyo) ,  IGARASHI N (Keio Univ., Tokyo) ,  WADA N (Keio Univ., Tokyo) ,  FUJII M (Keio Univ., Tokyo) ,  KAMEYAMA K (Keio Univ., Tokyo) ,  OKADA Y (Keio Univ., Tokyo) ,  KUMAI K (Keio Univ., Tokyo) ,  KITAJIMA M (Keio Univ., Tokyo)
Material： Japanese Journal of Cancer Research  (Proceedings. Annual Meeting of the Japanese Cancer Association)
Volume： 93  Issue： 7  Page： 834-841  Publication year： Jul. 31, 2002 
JST Material Number： F0633A  ISSN： 0910-5050  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibitor ,...
Semi thesaurus term： マリマスタット ,...

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JST classification (2)： Basic oncology in general  (GE02010R) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (2)： Mitomycin ,  Marimastat

Reference (34)：

• LIOTTA, L. A. Cancer metastasis and angiogenesis; an imbalance of positive and neoativ regulation. Cell. 1991, 64, 327-336
• STEWARD, W. P. Marimastat (BB2516) : current status of development. Cancer Chemother. Pharmacol. 1999, 43, Suppl, S56-S60
• IGARASHI, N. Preventive effect of matrix metalloproteinase inhibitor, R-94138, in combination with mitomycin C or cisplatin on peritoneal dissemination of human gastric cancer cell line TMK-1 in nude mice. Jpn. J. Cancer Res. 1999, 90, 116-121
• PRONTERA, C. Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastasis in mice bearing Lewis lung carcinoma. Int. J. Cancer. 1999, 81, 761-766
• GIACAZZI, R. Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma zenografts. Clin. Cancer Res. 1998, 4, 985-992

Terms in the title (5)： マトリックスメタロプロテアーゼ阻害剤 ,  マリマスタット ,  ヌードマウス ,  胃癌 ,  腹腔