Art

J-GLOBAL ID：200902162513099098   Reference number：98A0926511

Evidence for new non-steroidal human aromatase inhibitors and comparison with equine aromatase inhibition for an understanding of the mammalian active site.

新規非ステロイド性ヒトアロマターゼ阻害剤の証拠およびほ乳類活性部位解明のためのウマアロマターゼ阻害との比較

Author (9)： AUVRAY P (Univ. Caen, Caen, FRA) ,  MOSLEMI S (Univ. Caen, Caen, FRA) ,  SOURDAINE P (Univ. Caen, Caen, FRA) ,  GALOPIN S (Univ. Caen, Caen, FRA) ,  SERALINI G-E (Univ. Caen, Caen, FRA) ,  ENGUEHARD C (Lab. Pharmacochimie, Caen, FRA) ,  BUREAU R (Lab. Pharmacochimie, Caen, FRA) ,  SONNET P (Lab. Pharmacochimie, Caen, FRA) ,  RAULT S (Lab. Pharmacochimie, Caen, FRA)
Material： European Journal of Medicinal Chemistry  (Eur J Med Chem)
Volume： 33  Issue： 6  Page： 451-462  Publication year： Jun. 1998 
JST Material Number： E0845A  ISSN： 0223-5234  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Aromatase ,...
Semi thesaurus term： molecular model

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JST classification (2)： Basic research of drugs acting on endocrine system and reproductive organ  (GW10010K) ,  Indenes  (CF06030O)

Substance index (16)： 2,3-Dihydro-3-(trifluoroacetylamino)-5-methoxy-1H-indene-1-one ,  2,3-Dihydro-3-(trifluoroacetylamino)-5,6-dimethoxy-1H-indene-1-one ,  2,3-Dihydro-3-(trifluoroacetylamino)-5,6,7-trimethoxy-1H-indene-1-one ,  2,3-Dihydro-2-(3-methoxybenzylidene)-3-(trifluoroacetylamino)-5,6,7-trimethoxy-1H-indene-1-one ,  2,3-Dihydro-2-(3,4-dimethoxybenzylidene)-3-(trifluoroacetylamino)-5-methoxy-1H-indene-1-one ,  2,3-Dihydro-2-(3,4-dimethoxybenzylidene)-3-(trifluoroacetylamino)-5,6-dimethoxy-1H-indene-1-one ,  2,3-Dihydro-2-(3,4,5-trimethoxybenzylidene)-3-(trifluoroacetylamino)-5,6,7-trimethoxy-1H-indene-1-one ,  2,3-Dihydro-2-(3-pyridylmethylene)-3-(trifluoroacetylamino)-5-methoxy-1H-indene-1-one ,  2,3-Dihydro-2-(3-pyridylmethylene)-3-(trifluoroacetylamino)-5,6-dimethoxy-1H-indene-1-one ,  2,3-Dihydro-2-(4-pyridylmethylene)-3-(trifluoroacetylamino)-5,6-dimethoxy-1H-indene-1-one ,  2-(3-Pyridylmethyl)-3-amino-5-methoxy-1H-indene-1-one ,  2-(3-Pyridylmethyl)-3-amino-5,6,7-trimethoxy-1H-indene-1-one ,  2-(4-Pyridylmethyl)-3-amino-5-methoxy-1H-indene-1-one ,  2-(4-Pyridylmethyl)-3-amino-5,6-dimethoxy-1H-indene-1-one ,  2-(4-Pyridylmethyl)-3-amino-5,6,7-trimethoxy-1H-indene-1-one ,  2,3-Dihydro-2-(4-pyridylmethylene)-5-methoxy-1H-indene-1-one

Terms in the title (7)： ステロイド ,  ヒト ,  アロマターゼ阻害剤 ,  証拠 ,  ほ乳類 ,  活性部位 ,  阻害