Art

J-GLOBAL ID：200902162734252303   Reference number：03A0041125

Investigation into the usefulness and adverse events of CDDP, 5-FU and dl-Leucovorin(PFL-therapy) for advanced colorectal cancer.

進行性大腸腫ように対するCDDP,5-FUおよびdl-ロイコボリン(PFL療法)の有用性および副作用に関する研究

Author (9)： OKABE S (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  ISHIKAWA T (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  TANAMI H (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  KUWABARA H (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  FUKAHARA T (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  UDAGAWA M (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  OOTSUKASA S (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  ARAI T (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  IWAI T (Tokyo Medical and Dental Univ., Tokyo, JPN)
Material： Journal of Medical and Dental Sciences  (J Med Dent Sci)
Volume： 49  Issue： 2  Page： 77-84  Publication year： Jun. 2002 
JST Material Number： F0606A  ISSN： 1342-8810  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *colorectal neoplasm ,...
Semi thesaurus term： dichlorodiammine platinum ,...

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JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Substance index (2)： (+-)-5-Formyltetrahydrofolic acid ,  Fluorouracil

Reference (31)：

• 1. Wolmark N, Rockette H, Wickerham DL, et al. Adjuvant therapy of Dukes' A, B, and C adenocarcinoma of the colon with portal-vein fluorouracil hepatic infusion: preliminary results of\nNational Surgical Adjuvant Breast and Bowel Project Protocol C-02. J Clin Oncol 1990; 8: 1466-1475.
• 2. O'Connell MJ. A phase lll trial of 5-fluorouracil and leucovorin in the treatment of advanced colorectal cancer. A Mayo Clinic/North Central Cancer Treatment Group study. Cancer 1989; 63: 1026-1030.
• 3. Arbuck SG. Overview of clinicai trials using 5-fluorouracil and leucovorin for the treatment of colorectal cancer. Cancer 1989; 63: 1036-1044.
• 4. O'Connell MJ, Gunderson LL. Adjuvant therapy for adenocarcinoma of the rectum. World J Surg 1992; 16: 510-515.
• 5. Chu E, Grem JL, Johnston PG, et al. New concepts for the development and use of antifolates. Stem Cells 1996; 14: 41-46.

Terms in the title (8)： 大腸腫よう ,  CDDP ,  5-FU ,  dl-ロイコボリン ,  療法 ,  有用性 ,  副作用 ,  研究